IGF1 active protein
IGF1 protein
Gene Names
IGF1; IGFI; IGF-I; IGF1A
Purity
> 98% pure
Synonyms
IGF1; N/A; IGF1 protein; IGF 1 protein; IGF 1; IGF-1 protein; Insulin-like Growth Factor-1 protein; IGF-1A protein; Somatamedin C protein; IGF-1; IGF1 active protein
Host
Human
Purity/Purification
> 98% pure
Form/Format
Lyophilized with no additives. DO NOT VORTEX. Reconstitute in laboratory grade water to a concentration of 0.1 - 1.0 mg/ml.
Sequence
Region of IGF1 protein corresponding to amino acids GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPAKSA.
Sequence Length
21
Protein Type
Recombinant
Biological Significance
The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor.
Bioactivity
The ED50 was determined by a cell proliferation assay using FDC-P1 cells is 2.0 ng/ml, corresponding to a specific activity of 5 x 10^5 units/mg.
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Expression System
E Coli
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for IGF1 active protein
Purified recombinant Human IGF1 protein
Product Categories/Family for IGF1 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
2,410 Da
NCBI Official Full Name
insulin-like growth factor-I, partial
NCBI Official Synonym Full Names
insulin-like growth factor 1 (somatomedin C)
NCBI Official Symbol
IGF1
NCBI Official Synonym Symbols
IGFI; IGF-I; IGF1A
NCBI Protein Information
insulin-like growth factor I
UniProt Protein Name
Insulin-like growth factor-I
UniProt Gene Name
IGF1
UniProt Entry Name
Q6LD41_HUMAN
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Product Notes
The IGF1 igf1 (Catalog #AAA75399) is an Active Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Region of IGF1 protein correspond ing to amino acids GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPAKSA. It is sometimes possible for the material contained within the vial of "IGF1, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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