SDS-PAGE
IL22BP / IL22RA2 active protein
Recombinant Human IL22BP / IL22RA2 Protein (His tag)
Gene Names
IL22RA2; CRF2X; CRF2-10; CRF2-S1; IL-22BP; IL-22RA2; ZCYTOR16; IL-22R-alpha-2
Purity
> 95 % as determined by reducing SDS-PAGE
Synonyms
IL22BP / IL22RA2; N/A; Recombinant Human IL22BP / IL22RA2 Protein (His tag); IL22RA2, CRF2-10, CRF2-S1, CRF2X, IL-22BP, MGC150509, MGC150510, ZCYTOR16; IL22BP / IL22RA2 active protein
Host
Human
Purity/Purification
> 95 % as determined by reducing SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4, 5% Trehalose, 5% Mannitol, 0.01% Tween-80.
Sequence
Met 1-Pro 231
Sequence Length
231
Expression Host
HEK293 Cells
Endotoxin
< 1.0 EU per ug of the protein as determined by the LAL method
Tag
C-His
Bio Activity
Immobilized IL22BP-His at 10ug/ml (100 ul/well) can bind biotinylated IL22, The EC50 of biotinylated ILL22 is 1.78-4.14 ng/ml
Reconstitution
We recommend that the vial be centrifuged to opening to bring the contents to the bottom. Do not mix by vortex. It is recommended that sterile water(80ul) be added to the vial to prepare a stock solution of 0.25mg/mL. Concentration is measured by UV-Vis.
Preparation and Storage
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at <-20°C for 3 months. This product is provided as lyophilized powder which is shipped with blue ice.
SDS-PAGE
SDS-PAGE
Related Product Information for IL22BP / IL22RA2 active protein
Background: Interleukin-22 receptor subunit alpha-2 (IL-22RA2), also known as interleukin-22-binding protein (IL-22BP), is a subunit of the receptor for interleukin 22. IL-22BP belongs to the type I I cytokine receptor family and contains 3 fibronectin type -III domains. IL-22BP/IL-22RA2 is expressed in a range of tissues, including those in the digestive, female reproductive, and immune systems. It is expressed in placenta, spleen, breast, skin and lung. It is also detected in intestinal tract, testis, brain, heart and thymus. The dominant cell types expressing IL-22BP/IL-22RA2 were mononuclear cells and epithelium. IL-22BP/IL-22RA2 may play an important role as an IL-22 antagonist in the regulation of inflammatory responses. Interleukin-22 (IL-22) is a member of IL-10 family. It is produced by T cells and induces the production of acute-phase reactants. IL-22 plays important roles in immune response through activation of the STAT 3 signal transduction pathway. Two types of IL-22-binding receptor have been discovered, a membrane-bound receptor and a soluble receptor.
Description: A DNA sequence encoding the human IL22RA2 isoform 2 (NP_851826.1) (Met 1-Pro 231) was expressed, fused with a polyhistidine tag at the C-terminus.
Description: A DNA sequence encoding the human IL22RA2 isoform 2 (NP_851826.1) (Met 1-Pro 231) was expressed, fused with a polyhistidine tag at the C-terminus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Molecular Weight: 26.1 kDa
AP Molecular Weight: 50-55 kDa
AP Molecular Weight: 50-55 kDa
NCBI Official Full Name
interleukin-22 receptor subunit alpha-2 isoform 2
NCBI Official Synonym Full Names
interleukin 22 receptor subunit alpha 2
NCBI Official Symbol
IL22RA2
NCBI Official Synonym Symbols
CRF2X; CRF2-10; CRF2-S1; IL-22BP; IL-22RA2; ZCYTOR16; IL-22R-alpha-2
NCBI Protein Information
interleukin-22 receptor subunit alpha-2
UniProt Protein Name
Interleukin-22 receptor subunit alpha-2
UniProt Gene Name
IL22RA2
UniProt Synonym Gene Names
IL-22 receptor subunit alpha-2; IL-22R-alpha-2; IL-22RA2; CRF2-10; CRF2-S1; IL-22BP; IL22BP
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Product Notes
The IL22BP / IL22RA2 il22ra2 (Catalog #AAA173554) is an Active Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Met 1-Pro 231. It is sometimes possible for the material contained within the vial of "IL22BP / IL22RA2, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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