IF (Immunofluorescence)
(Immunofluorescence analysis of COS7 cells, using HTR2B Antibody. The picture on the right is blocked with the synthesized peptide.)
anti-Human HTR2B Antibody | anti-HTR2B antibody
HTR2B Antibody
Gene Names
HTR2B; 5-HT2B; 5-HT-2B; 5-HT(2B)
Reactivity
Human
Applications
ELISA, Immunofluorescence, Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Synonyms
HTR2B; N/A; HTR2B Antibody; HTR2B;5-hydroxytryptamine receptor 2B;5-HT-2B;5-HT2B;Serotonin receptor 2B; anti-HTR2B antibody
Reactivity
Human
Specificity
HTR2B Antibody detects endogenous levels of total HTR2B
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
481
Applicable Applications for anti-HTR2B antibody
ELISA, IF (Immunofluorescence), WB (Western Blot)
Immunogen
The antiserum was produced against synthesized peptide derived from human HTR2B. AA range:15-64
Function
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Interacts with MPDZ.,tissue specificity:Detected in most peripheral organs. Only low expression levels were found in the brain.
Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome.
Expression
Ubiquitous. Detected in liver, kidney, heart, pulmonary artery, and intestine. Detected at lower levels in blood, placenta and brain, especially in cerebellum, occipital cortex and frontal cortex.
Preparation and Storage
Store at -15°C to -25°C/1 year (Do not lower than -25°C).
IF (Immunofluorescence)
(Immunofluorescence analysis of COS7 cells, using HTR2B Antibody. The picture on the right is blocked with the synthesized peptide.)
IF (Immunofluorescence)
(Immunofluorescence analysis of COS7 cells, using HTR2B Antibody. The picture on the right is blocked with the synthesized peptide.)
WB (Western Blot)
(Dissecting the novel abilities of aripiprazole: The generation of anti-colorectal cancer effects by targeting G ? q via HTR2B. Changhua Hu WB Human FHC cell,HT29 cell,LoVo cell,SW480 cell,HCT116 cell.)
WB (Western Blot)
(Dissecting the novel abilities of aripiprazole: The generation of anti-colorectal cancer effects by targeting G ? q via HTR2B. Changhua Hu WB Human FHC cell,HT29 cell,LoVo cell,SW480 cell,HCT116 cell.)
WB (Western Blot)
(Western blot analysis of lysates from HT-29, 293, and HeLa cells, using HTR2B Antibody. The lane on the right is blocked with the synthesized peptide.)
WB (Western Blot)
(Western blot analysis of lysates from HT-29, 293, and HeLa cells, using HTR2B Antibody. The lane on the right is blocked with the synthesized peptide.)
Related Product Information for anti-HTR2B antibody
This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
54kDa
NCBI Official Full Name
5-hydroxytryptamine receptor 2B isoform 1
NCBI Official Synonym Full Names
5-hydroxytryptamine receptor 2B
NCBI Official Symbol
HTR2B
NCBI Official Synonym Symbols
5-HT2B; 5-HT-2B; 5-HT(2B)
NCBI Protein Information
5-hydroxytryptamine receptor 2B
UniProt Protein Name
5-hydroxytryptamine receptor 2B
UniProt Gene Name
HTR2B
UniProt Synonym Gene Names
5-HT-2B; 5-HT2B
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Product Notes
The HTR2B htr2b (Catalog #AAA267949) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The HTR2B Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HTR2B can be used in a range of immunoassay formats including, but not limited to, ELISA, IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the HTR2B htr2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HTR2B, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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