Cardiac Troponin-T Native Protein | TNNT2 native protein
Human Cardiac Troponin-T
Gene Names
TNNT2; CMH2; RCM3; TnTC; cTnT; CMD1D; CMPD2; LVNC6
Purity
Greater than 95.0% as determined by SDS-PAGE.
Synonyms
Cardiac Troponin-T; N/A; Human Cardiac Troponin-T; TnT Human; Cardiac Troponin T Human; Troponin T cardiac muscle; TnTc; Cardiac muscle troponin T; cTnT; TNNT2; CMH2; CMPD2; MGC3889; Troponin-T; TNNT2 native protein
Host
Human Cardiac Tissue
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Form/Format
Human Cardiac Troponin T in 6M Urea, 250 mM NaCI, 50 mM Tris-HCI, 15mM Beta-mercaptoethanol, 1mM EDTA, pH 7.2
Sequence Length
295
Physical Appearance
Sterile Filtered colorless liquid formulation (1.88 mg/mL).
Human Virus Test
Blood samples from tissue donors used in the manufacture of this product tested negative for HIV-1,2, HbsAg, HCV and RPR/STS.
Preparation and Storage
Human TnT although stable at 10°C for 7 days, should be stored desiccated below -18°C.
Please prevent freeze-thaw cycles.
Please prevent freeze-thaw cycles.
Related Product Information for TNNT2 native protein
Description: Human Cardiac Troponin T produced from Human Cardiac Tissue, having a molecular weight of approximately 35 kDa.
The Cardiac troponin-T is purified using a combination of ion-exchange and affinity chromatography steps.
Introduction: Troponin-T is one of three subunits that form the troponin complex of the thin filaments of striated muscle, it regulates muscle contraction in response to alterations in intracellular calcium ion concentration. TnTc is expressed only in the heart and has proved to be a specific biomarker for heart disease. Mutations in TNNT2 are associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Alternative splicing results in many tissue-specific isoforms.
The Cardiac troponin-T is purified using a combination of ion-exchange and affinity chromatography steps.
Introduction: Troponin-T is one of three subunits that form the troponin complex of the thin filaments of striated muscle, it regulates muscle contraction in response to alterations in intracellular calcium ion concentration. TnTc is expressed only in the heart and has proved to be a specific biomarker for heart disease. Mutations in TNNT2 are associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Alternative splicing results in many tissue-specific isoforms.
Product Categories/Family for TNNT2 native protein
References
Preliminary development of a DNA aptamer-magnetic bead capture electrochemiluminescence sandwich assay for brain natriuretic peptide. John G. Bruno, Alicia M. Richarte, Taylor Phillips (2014)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
troponin T, cardiac muscle isoform 1
NCBI Official Synonym Full Names
troponin T type 2 (cardiac)
NCBI Official Symbol
TNNT2
NCBI Official Synonym Symbols
CMH2; RCM3; TnTC; cTnT; CMD1D; CMPD2; LVNC6
NCBI Protein Information
troponin T, cardiac muscle; cardiomyopathy, dilated 1D (autosomal dominant); cardiomyopathy, hypertrophic 2; troponin T2, cardiac
UniProt Protein Name
Troponin T, cardiac muscle
UniProt Gene Name
TNNT2
UniProt Synonym Gene Names
TnTc; cTnT
UniProt Entry Name
TNNT2_HUMAN
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Product Notes
The TNNT2 tnnt2 (Catalog #AAA38442) is a Native Protein produced from Human Cardiac Tissue and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Cardiac Troponin-T, Native Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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