Bioactivity
GAS6 active protein
Recombinant Human GAS6 (C-6His)
Gene Names
GAS6; AXSF; AXLLG
Purity
>95% as determined by reducing SDS-PAGE
Synonyms
GAS6; N/A; Recombinant Human GAS6 (C-6His); AXLLG; AXLLGAXL stimulatory factor; AXSFAXL receptor tyrosine kinase ligand; Gas6; GAS-6; growth arrest-specific 6; growth arrest-specific protein 6; GAS6 active protein
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE
Form/Format
Supplied as a 0.2um filtered solution of PBS, 10% Glycerol, pH7.4.
Sequence
Ala31-Ala678
Species
Human
Tag
C-6His
Endotoxin
<1.0EU per ug as determined by the LAL method.
Protein Construction
Recombinant Human Growth Arrest-specific Protein 6 is produced by our Mammalian expression system and the target gene encoding Ala31-Ala678 is expressed with a 6His tag at the C-terminus.
Activity
Immobilized Human AXL-His at 10ug/ml (100ul/well) can bind Human GAS6-His* .*: Biotinylated by NHS-biotin prior to testing.The ED50 of Recombinant Human GAS6-His* is 0.04466 ug/ml.
Preparation and Storage
Store at < -20 degree C, stable for 6 months. Please minimize freeze-thaw cycles.
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20 degree C.
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20 degree C.
Bioactivity
Bioactivity
SDS-PAGE
SDS-PAGE
Related Product Information for GAS6 active protein
GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
Product Categories/Family for GAS6 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
79,677 Da
NCBI Official Full Name
growth arrest-specific protein 6 isoform 1
NCBI Official Synonym Full Names
growth arrest-specific 6
NCBI Official Symbol
GAS6
NCBI Official Synonym Symbols
AXSF; AXLLG
NCBI Protein Information
growth arrest-specific protein 6; AXL stimulatory factor; AXL receptor tyrosine kinase ligand
UniProt Protein Name
Growth arrest-specific protein 6
UniProt Gene Name
GAS6
UniProt Synonym Gene Names
AXLLG; GAS-6
UniProt Entry Name
GAS6_HUMAN
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Product Notes
The GAS6 gas6 (Catalog #AAA177950) is an Active Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Ala31-Ala6 78. It is sometimes possible for the material contained within the vial of "GAS6, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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