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product-image-AAA174597_SDS_PAGE15.jpg SDS-PAGE

Kallikrein 7 Active Protein | KLK7 active protein

Recombinant Human Kallikrein 7/KLK7 Protein (His Tag)

Gene Names
KLK7; hK7; SCCE; PRSS6
Purity
> 95 % as determined by reducing SDS-PAGE.
Synonyms
Kallikrein 7; N/A; Recombinant Human Kallikrein 7/KLK7 Protein (His Tag); Kallikrein-7; hK7; Serine Protease 6; Stratum Corneum Chymotryptic Enzyme; hSCCE; KLK7; PRSS6; SCCE; KLK7 active protein
Ordering
Host
Human Cells
Purity/Purification
> 95 % as determined by reducing SDS-PAGE.
Form/Format
Supplied as a 0.2 um filtered solution of 20mM HEPES, 150mM NaCl, pH 7.5.
Concentration
0.66 mg/mL. (varies by lot)
Sequence
Glu23-His252
Species
Human
Tag
C-6His
Endotoxin
< 1.0 EU per ug as determined by the LAL method.
Preparation and Storage
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
This product is provided as liquid. It is shipped with blue ice. Upon receipt, store it immediately at<-20°C.

SDS-PAGE

product-image-AAA174597_SDS_PAGE15.jpg SDS-PAGE
Related Product Information for KLK7 active protein
Human Kallikrein 7 is a member of the tissue kallikrein family of extracellular serine proteases that is made up of 15 members. It is predominantly expressed in the skin. A major physiological function of Kallikrein 7 is to regulate the desquamation process (the shedding of corneocytes from the outer layer of the epidermis) through proteolysis of the intercellular adhesive structures between corneocytes. Dysregulation of Kallikrein 7 has been linked to several inflammatory skin diseases including atopic dermatitis, psoriasis, and Netherton syndrome. Studies have shown that Kallikrein 5 is a potential physiological activator for Kallikrein 7. The proform of Kallikrein 7 can be activated by thermolysin.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Molecular Mass: 26.2kDa
Actual Protein Molecular Mass: 30kDa
NCBI Official Full Name
kallikrein-7 isoform 2
NCBI Official Synonym Full Names
kallikrein related peptidase 7
NCBI Official Symbol
KLK7
NCBI Official Synonym Symbols
hK7; SCCE; PRSS6
NCBI Protein Information
kallikrein-7
UniProt Protein Name
Kallikrein-7
UniProt Gene Name
KLK7
UniProt Synonym Gene Names
PRSS6; SCCE; hK7; hSCCE

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Product Notes

The KLK7 klk7 (Catalog #AAA174597) is an Active Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Glu23-His2 52. It is sometimes possible for the material contained within the vial of "Kallikrein 7, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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