Human Bh3-Interacting Domain Death Agonist, BID ELISA Kit | BID elisa kit

Human Bh3-Interacting Domain Death Agonist, BID Primacu ELISA Kit

Cat. Num. AAA124391

• Gene Names: BID; FP497
• Reactivity: Human
• Synonyms: Bh3-Interacting Domain Death Agonist, BID; N/A; Human Bh3-Interacting Domain Death Agonist, BID Primacu ELISA Kit; BH3-interacting domain death agonist; BID; BID elisa kit

• Reactivity: Human
• Assay Type: Sandwich
• Samples: Serum, plasma, cell culture supernates
• Detection Range: 7.81-500pg/mL
• Sensitivity: 1.48pg/mL
• Standard Solution: 5ng/mL
• Assay Time: 3.5h

• Preparation and Storage: Store at 2-8 degree C

Standard Curve (Sample)

(Typical Testing Data/Standard Curve (for reference only))

Related Product Information for BID elisa kit

The BH3 interacting domain death agonist (BID) is a pro-apoptotic member of the Bcl-2 protein family, which contains only the BH3 domain, and is required for its interaction with the Bcl-2 family proteins and for its pro-death activity. BID is important to cell death mediated by these proteases and thus is the sentinel to protease-mediated death signals. Recent studies further indicate that Bid may be more than just a killer molecule, it could be also involved in the maintenance of genomic stability by engaging at mitosis checkpoint. BID is an integrating key regulator of the intrinsic death pathway that amplifies caspase-dependent and caspase-independent execution of neuronal apoptosis. Therefore pharmacological inhibition of BID provides a promising therapeutic strategy in neurological diseases where programmed cell death is prominent. BID is activated by Caspase 8 in response to Fas/TNF-R1 death receptor activation. Activated BID is translocated to mitochondria and induces cytochrome c release, which in turn activates downstream caspases. BID action has been proposed to involve the mitochondrial re-location of its truncated form, tBid, to facilitate the release of apoptogenic proteins like cytochrome c.

Product Categories/Family for BID elisa kit

Primacu ELISA Kit; Cancer; Cell biology; Metabolism

NCBI and Uniprot Product Information

• NCBI GI #: 4557361
• NCBI GeneID: 637
• NCBI Accession #: NP_001187.1
• NCBI GenBank Nucleotide #: NM_001196.3
• UniProt Accession #: P55957; Q549M7; Q71T04; Q7Z4M9; Q8IY86
• Molecular Weight: 21,995 Da
• NCBI Official Full Name: BH3-interacting domain death agonist isoform 2
• NCBI Official Synonym Full Names: BH3 interacting domain death agonist
• NCBI Official Symbol: BID
• NCBI Official Synonym Symbols: FP497
• NCBI Protein Information: BH3-interacting domain death agonist; p22 BID; BID isoform Si6; BID isoform L(2); BID isoform ES(1b); desmocollin type 4; apoptic death agonist; Human BID coding sequence
• UniProt Protein Name: BH3-interacting domain death agonist
• UniProt Gene Name: BID
• UniProt Synonym Gene Names: BID
• UniProt Entry Name: BID_HUMAN