Human CD31/PECAM-1 ELISA Kit | CD31/PECAM-1 elisa kit
Human CD31/PECAM-1 ELISA Kit
Reactivity
Human
Synonyms
CD31/PECAM-1; N/A; Human CD31/PECAM-1 ELISA Kit; CD31 ELISA Kit, Human; platelet/endothelial cell adhesion molecule 1; CD31/EndoCAM ELISA Kit, Human; endoCAM ELISA Kit, Human; GPIIA' ELISA Kit, Human; PECA1 ELISA Kit, Human; PECAM-1 ELISA Kit, Human; CD31/PECAM-1 elisa kit
Reactivity
Human
Specificity
For the quantitative determination of Human CD31/PECAM-1 concentration in serum, urine and saliva.
Assay Type
Solid Phase Sandwich ELISA (quantitative)
Sample Types
Serum, Urine, Saliva
Detection Range
218.75-14000pg/mL
Sensitivity
38.43pg/mL
Conjugation
HRP
Interference
Preparations of the following factors at 200ng/mL in a mid-range recombinant Human CD31 control were assayed for interference. No significant interference was observed.
Materials Provided
1. 96 well microplate coated with Capture Antibody
2. Detection Antibody conjugated to HRP
3. Standards
4. Wash Buffer Concentrate
5. Dilution Buffer Concentrate
6. Color Reagent A
7. Color Reagent B
8. Stop Solution
2. Detection Antibody conjugated to HRP
3. Standards
4. Wash Buffer Concentrate
5. Dilution Buffer Concentrate
6. Color Reagent A
7. Color Reagent B
8. Stop Solution
Related Product Information for CD31/PECAM-1 elisa kit
Background: The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin alphavbeta3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development.
References
Deaglio S, et al. (2000) CD38/CD31, a receptor/ligand system ruling adhesion and signaling in human leukocytes. Chem Immunol. 75: 99-120.
Kohler S, et al. (2009) Life after the thymus: CD31+ and CD31- human naive CD4+ T-cell subsets. Blood. 113(4): 769-74.
Kohler S, et al. (2009) Life after the thymus: CD31+ and CD31- human naive CD4+ T-cell subsets. Blood. 113(4): 769-74.
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Product Notes
The Human CD31/PECAM-1 (Catalog #AAA258334) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA258334 ELISA Kit recognizes Human CD31/PECAM-1. It is sometimes possible for the material contained within the vial of "CD31/PECAM-1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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