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product-image-AAA124370_SC15.jpg Standard Curve (Sample) (Typical Testing Data/Standard Curve (for reference only))

Human Ephrin Type-B Receptor 6, EPHB6 ELISA Kit | EPHB6 elisa kit

Human Ephrin Type-B Receptor 6, EPHB6 Primacu ELISA Kit

Gene Names
EPHB6; HEP
Reactivity
Human
Synonyms
Ephrin Type-B Receptor 6, EPHB6; N/A; Human Ephrin Type-B Receptor 6, EPHB6 Primacu ELISA Kit; Ephrin type-B receptor 6; EphB6; EPHB6 elisa kit
Ordering
Reactivity
Human
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
9.38-600pg/mL
Sensitivity
2.82pg/mL
Standard Solution
6ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C

Standard Curve (Sample)

(Typical Testing Data/Standard Curve (for reference only))

product-image-AAA124370_SC15.jpg Standard Curve (Sample) (Typical Testing Data/Standard Curve (for reference only))
Related Product Information for EPHB6 elisa kit
Ephrins are divided into the ephrin-A (EFNA) class and the ephrin-B (EFNB) class based on their structures and sequence relationships. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB6 is an unusual Eph receptor, lacking catalytic capacity due to alterations in its kinase domain. Interestingly, increased metastatic activity is associated with reduced EphB6 receptor expression in several tumor types, including breast cancer. This emphasizes the potential of EphB6 to act as a suppressor of cancer aggressiveness. EphB6 suppress cancer invasiveness through c-Cbl-dependent signaling, morphologic changes, and cell attachment and indicate that EphB6 may represent a useful prognostic marker and a promising target for therapeutic approaches. EphB6 can both positively and negatively regulate cell adhesion and migration, and suggest that tyrosine phosphorylation of the receptor by an Src family kinase acts as the molecular switch for the functional transition. In addition, Ephrin-B2 may be a physiological ligand for the EphB6 receptor.
Product Categories/Family for EPHB6 elisa kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
110,700 Da
NCBI Official Full Name
ephrin type-B receptor 6
NCBI Official Synonym Full Names
EPH receptor B6
NCBI Official Symbol
EPHB6
NCBI Official Synonym Symbols
HEP
NCBI Protein Information
ephrin type-B receptor 6; tyrosine-protein kinase-defective receptor EPH-6
UniProt Protein Name
Ephrin type-B receptor 6
UniProt Gene Name
EPHB6
UniProt Entry Name
EPHB6_HUMAN

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Product Notes

The Human EPHB6 ephb6 (Catalog #AAA124370) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124370 ELISA Kit recognizes Human EPHB6. It is sometimes possible for the material contained within the vial of "Ephrin Type-B Receptor 6, EPHB6, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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