Standard Curve (Sample)
(Representative standard curve for IL-15 ELISA. IL-15 was diluted in serial two-fold steps in Sample Diluent.)
Human IL-15 ELISA Kit | IL-15 elisa kit
Human IL-15 ELISA KIT
Gene Names
IL15; IL-15
Reactivity
Human
Synonyms
IL-15; N/A; Human IL-15 ELISA KIT; Human IL-15; IL-15 elisa kit
Reactivity
Human
Specificity
Natural and recombinant Human IL-15 Ligand
Assay Type
Solid Phase Sandwich ELISA
Samples
Cell culture supernatant, serum, plasma (EDTA, citrate, heparin)
Detection Range
7.8-500pg/mL
Sensitivity
4pg/mL
Assay Time
3 hours
Sample Volume
20 uL
Detection Method
Colorimetric
Preparation and Storage
Store at 4 degree C
Standard Curve (Sample)
(Representative standard curve for IL-15 ELISA. IL-15 was diluted in serial two-fold steps in Sample Diluent.)
Standard Curve (Sample)
(Representative standard curve for IL-15 ELISA. IL-15 was diluted in serial two-fold steps in Sample Diluent.)
Related Product Information for IL-15 elisa kit
Interleukin 15 (IL-15) is a 14 kDa cytokine that is structurally and functionally related to IL- 2 (1-3). Mature human IL-15 shares 70% amino acid sequence identity with mouse and rat IL-15. Alternate splicing generates isoforms of IL-15 with either a long or short signal peptide (LSP or SSP), and the SSP isoform is retained intracellularly (4). IL-15 associates with IL-15 Ra in the endoplasmic reticulum, and this complex is expressed on the cell surface (5, 6). The dominant mechanism of IL-15 action is known as transpresentation in which IL-15 and IL-15 Ra are coordinately expressed on the surface of one cell and interact with complexes of IL-2 Rb/gc on adjacent cells (7). This enables cells to respond to IL-15 even if they do not express IL-15 Ra (6, 8). Consistent with its shared use of IL-2 receptor subunits, IL-15 induces IL-2-like effects in lymphocyte development and homeostasis (3). It is particularly important for the maintenance and activation of NK cells and CD8+ memory T cells (3). IL-15 also exerts pleiotropic effects on other hematopoietic cells and nonimmune cells (2). Ligation of membraneassociated IL-15/IL-15Ra complexes induces reverse signaling that promotes cellular adhesion, tyrosine phosphorylation of intracellular proteins, and cytokine secretion by the IL-15/IL-15Ra expressing cells (9, 10).
NCBI and Uniprot Product Information
Similar Products
Product Notes
The Human IL-15 il15 (Catalog #AAA309879) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA309879 ELISA Kit recognizes Human IL-15. It is sometimes possible for the material contained within the vial of "IL-15, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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