Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Human Immunoglobulin Alpha Fc Receptor, FCAR ELISA Kit | FCAR elisa kit
Human Immunoglobulin Alpha Fc Receptor, FCAR Primacu ELISA Kit
Gene Names
FCAR; CD89; FcalphaRI; CTB-61M7.2
Reactivity
Human
Synonyms
Immunoglobulin Alpha Fc Receptor, FCAR; N/A; Human Immunoglobulin Alpha Fc Receptor, FCAR Primacu ELISA Kit; Immunoglobulin alpha Fc receptor; CD89; FCAR elisa kit
Reactivity
Human
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
7.81-500pg/mL
Sensitivity
2.43pg/mL
Standard Solution
5ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C
Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Related Product Information for FCAR elisa kit
FCAR, also called FcalphaRI or CD89, is a type I transmembrane receptor for Fc region of IgA which is the most abundant immunoglobulin in mucosal areas but is only the second most common antibody isotype in serum. This receptor is present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, especially phagocytes located in mucosal areas. Upon ligand IgA binding, FcalphaRI associates with the FcR gamma signaling molecule bearing the immunoreceptor tyrosine-based activation motif (ITAM) through a unique charge-based mechanism and triggers multiple cell-mediated immune responses. It has been reported that Fc RI is a dual-function receptor that can mediate both inflammatory and anti-inflammatory responses depending on the type of interaction with its ligand. Sustained aggregation of FCAR results in activation of target-cell functions such as antigen presentation and cytokine release. In contrast, Monomeric targeting with serum IgA or with a variety of anti-FcalphaRI Fab fragments triggers an inhibitory response and additionally induces apoptosis. FcalphaRI thus play an fundamental role in preventing tumor development and growth, as well as in controlling inflammation.
Product Categories/Family for FCAR elisa kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
28,343 Da
NCBI Official Full Name
Immunoglobulin alpha Fc receptor
NCBI Official Synonym Full Names
Fc fragment of IgA receptor
NCBI Official Symbol
FCAR
NCBI Official Synonym Symbols
CD89; FcalphaRI; CTB-61M7.2
NCBI Protein Information
immunoglobulin alpha Fc receptor
UniProt Protein Name
Immunoglobulin alpha Fc receptor
UniProt Gene Name
FCAR
UniProt Synonym Gene Names
CD89; IgA Fc receptor
Similar Products
Product Notes
The Human FCAR fcar (Catalog #AAA124388) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124388 ELISA Kit recognizes Human FCAR. It is sometimes possible for the material contained within the vial of "Immunoglobulin Alpha Fc Receptor, FCAR, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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