Human Interleukin-10, IL10 ELISA Kit | IL10 elisa kit

Human Interleukin-10, IL10 Primacu ELISA Kit

Cat. Num. AAA124349

• Gene Names: IL10; CSIF; TGIF; GVHDS; IL-10; IL10A
• Reactivity: Human
• Synonyms: Interleukin-10, IL10; N/A; Human Interleukin-10, IL10 Primacu ELISA Kit; Interleukin-10; IL-10; IL10 elisa kit

• Reactivity: Human
• Assay Type: Sandwich
• Samples: Serum, plasma, cell culture supernates
• Detection Range: 14.06-900pg/mL
• Sensitivity: 2.6pg/mL
• Standard Solution: 9ng/mL
• Assay Time: 3.5h

• Preparation and Storage: Store at 2-8 degree C

Standard Curve (Sample)

(Typical Testing Data/Standard Curve (for reference only))

Related Product Information for IL10 elisa kit

IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by monocytes and to a lesser extent by lymphocytes. IL-10 is mainly expressed in monocytes and Type 2 T helper cells (TH2), mast cells, CD4+CD25+Foxp3+ regulatory T cells, and also in a certain subset of activated T cells and B cells. IL-10 has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. The importance of interleukin 10 for counteracting excessive immunity in the human body is revealed by the fact that patients with Crohn's disease react favorably towards treatment with bacteria producing recombinant IL-10. IL-10 inhibits the synthesis of some cytokines, including IFN-gamma, IL-2, IL-3, TNF, and GM-CSF produced by activated macrophages and by helper T-cells. It also displays a potent ability to suppress the antigen-presentation capacity of antigen-presenting cells. However, it is also stimulatory towards certain T cells and mast cells and stimulates B cell maturation and antibody production. Cancer Immunotherapy Immune Checkpoint Immunotherapy Targeted Therapy

Product Categories/Family for IL10 elisa kit

Primacu ELISA Kit; Neuroscience; Cancer; Immunology

NCBI and Uniprot Product Information

• NCBI GI #: 124292
• NCBI GeneID: 3586
• UniProt Accession #: P22301
• Molecular Weight: 178
• NCBI Official Full Name: Interleukin-10
• NCBI Official Synonym Full Names: interleukin 10
• NCBI Official Symbol: IL10
• NCBI Official Synonym Symbols: CSIF; TGIF; GVHDS; IL-10; IL10A
• NCBI Protein Information: interleukin-10; T-cell growth inhibitory factor; cytokine synthesis inhibitory factor
• UniProt Protein Name: Interleukin-10
• UniProt Gene Name: IL10
• UniProt Synonym Gene Names: IL-10; CSIF
• UniProt Entry Name: IL10_HUMAN