Human Junctional Adhesion Molecule-Like, JAML ELISA Kit | JAML elisa kit
Human Junctional Adhesion Molecule-Like, JAML Primacu ELISA Kit
Gene Names
AMICA1; JAML; AMICA; Gm638; CREA7-1; CREA7-4
Reactivity
Human
Synonyms
Junctional Adhesion Molecule-Like, JAML; N/A; Human Junctional Adhesion Molecule-Like, JAML Primacu ELISA Kit; Junctional adhesion molecule-like; JAML; AMICA1; JAML elisa kit
Reactivity
Human
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
234.38-15000pg/mL
Sensitivity
72.34pg/mL
Standard Solution
150ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C
Related Product Information for JAML elisa kit
Junctional adhesion molecules (JAMs) are endothelial and epithelial adhesion molecules involved in the recruitment of circulating leukocytes to inflammatory sites. JAML (Junctional adhesion molecule-like), also known as AMICA1 (Adhesion molecule interacting with CXADR antigen 1), a protein related to the JAM family, is restricted to leukocytes and promotes their adhesion to endothelial cells. It contains 2 extracellular immunoglobulin-like domains, a transmembrane segment, and a cytoplasmic tail involved in activation signaling. Monocytic JAML/AMICA1 plays a critical role in regulating monocyte transendothelial migration (TEM) probably via binding to the endothelial coxsackie and adenovirus receptor (CAR) and other tight junction-associated adhesive molecules. The Expression of JAML/AMICA1 is restricted to the hematopoietic tissues with the exception of liver. JAML may function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, JAML/AMICA1 also enhances myeloid leukemia cell adhesion to endothelial cells.
Product Categories/Family for JAML elisa kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
40,136 Da
NCBI Official Full Name
junctional adhesion molecule-like isoform 1
NCBI Official Synonym Full Names
adhesion molecule, interacts with CXADR antigen 1
NCBI Official Symbol
AMICA1
NCBI Official Synonym Symbols
JAML; AMICA; Gm638; CREA7-1; CREA7-4
NCBI Protein Information
junctional adhesion molecule-like; adhesion molecule AMICA; dendritic-cell specific protein CREA7-1; dendritic-cell specific protein CREA7-4; adhesion molecule interacting with CXADR antigen 1
UniProt Protein Name
Junctional adhesion molecule-like
UniProt Gene Name
AMICA1
UniProt Synonym Gene Names
JAML; UNQ722/PRO1387
UniProt Entry Name
JAML1_HUMAN
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Product Notes
The Human JAML amica1 (Catalog #AAA124088) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124088 ELISA Kit recognizes Human JAML. It is sometimes possible for the material contained within the vial of "Junctional Adhesion Molecule-Like, JAML, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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