Human Latent Transforming Growth Factor beta Binding Protein 2 (LTBP2) ELISA Kit | LTBP2 elisa kit
Human Latent Transforming Growth Factor beta Binding Protein 2 (LTBP2) ELISA Kit
Gene Names
LTBP2; WMS3; GLC3D; LTBP3; MSPKA; MSTP031; C14orf141
Reactivity
Human
Synonyms
Latent Transforming Growth Factor beta Binding Protein 2 (LTBP2); N/A; Human Latent Transforming Growth Factor beta Binding Protein 2 (LTBP2) ELISA Kit; LTBP2; C14orf141; GLC3D; LTBP3; MSTP031; LTBP2 elisa kit
Reactivity
Human
Specificity
Human Latent transforming growth factor beta binding protein 2 (LTBP2) ELISA Kit has high sensitivity and excellent specificity for detection of Human LTBP2. No significant cross-reactivity or interference between Human LTBP2 and analogues was observed.
Sequence Length
1821
Assay Type
Sandwich ELISA (Quantitative)
Samples
Cell Culture Supernatants, Serum, Plasma, Other Biological Fluids
Detection Method
Colorimetric
Usage Notes
* Do not mix components from different kit lots or use reagents beyond the kit expiration date.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for LTBP2 elisa kit
Description: This Human Latent transforming growth factor beta binding protein 2 (LTBP2) ELISA Kit employs a two-site sandwich ELISA to quantitate LTBP2 in samples. An antibody specific for LTBP2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any LTBP2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for LTBP2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of LTBP2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background: LTBP2 belongs to the family of latent transforming growth factor (TGF)-beta binding proteins (LTBP), which are extracellular matrix proteins with multi-domain structure. This protein is the largest member of the LTBP family possessing unique regions and with most similarity to the fibrillins. It has thus been suggested that it may have multiple functions: as a member of the TGF-beta latent complex, as a structural component of microfibrils, and a role in cell adhesion.LTBP2 has approximately 45% amino acid identity to LTBP1 and 25% identity to fibrillin-1 (FBN1) but unlike other LTBP family members does not bind to latent forms of TGFB. The C-terminal region of LTBP2 competes with LTBP1 for specific binding to the N-terminal region of FBN1, but not FBN6, in microfibrils.
Background: LTBP2 belongs to the family of latent transforming growth factor (TGF)-beta binding proteins (LTBP), which are extracellular matrix proteins with multi-domain structure. This protein is the largest member of the LTBP family possessing unique regions and with most similarity to the fibrillins. It has thus been suggested that it may have multiple functions: as a member of the TGF-beta latent complex, as a structural component of microfibrils, and a role in cell adhesion.LTBP2 has approximately 45% amino acid identity to LTBP1 and 25% identity to fibrillin-1 (FBN1) but unlike other LTBP family members does not bind to latent forms of TGFB. The C-terminal region of LTBP2 competes with LTBP1 for specific binding to the N-terminal region of FBN1, but not FBN6, in microfibrils.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Latent-transforming growth factor beta-binding protein 2
NCBI Official Synonym Full Names
latent transforming growth factor beta binding protein 2
NCBI Official Symbol
LTBP2
NCBI Official Synonym Symbols
WMS3; GLC3D; LTBP3; MSPKA; MSTP031; C14orf141
NCBI Protein Information
latent-transforming growth factor beta-binding protein 2
UniProt Protein Name
Latent-transforming growth factor beta-binding protein 2
UniProt Gene Name
LTBP2
UniProt Synonym Gene Names
C14orf141; LTBP3; LTBP-2
UniProt Entry Name
LTBP2_HUMAN
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Product Notes
The Human LTBP2 ltbp2 (Catalog #AAA331917) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA331917 ELISA Kit recognizes Human LTBP2. It is sometimes possible for the material contained within the vial of "Latent Transforming Growth Factor beta Binding Protein 2 (LTBP2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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