Standard Curve (Sample)
Human LIFR ELISA Kit | LIFR elisa kit
Human LIFR ELISA Kit
Gene Names
LIFR; SWS; SJS2; STWS; CD118; LIF-R
Reactivity
Human
Applications
ELISA
Synonyms
LIFR; N/A; Human LIFR ELISA Kit; Leukemia inhibitory factor receptor; LIF receptor; LIF-R; CD118; LIFR elisa kit
Reactivity
Human
Specificity
The Human LIFR ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human LIFR proteins within the range of 156 pg/ml - 10000 pg/ml.
Sequence Length
1097
Samples
Serum, plasma
Sensitivity
Typically less than 10 pg/ml.
Applicable Applications for LIFR elisa kit
ELISA (Sandwich ELISA)
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Standard Curve (Sample)
Standard Curve (Sample)
Related Product Information for LIFR elisa kit
Principle of the Assay: The Human LIFR ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human LIFR in Cell Culture Supernatants, Serum, Plasma. This assay employs an antibody specific for Human LIFR coated on a 96-well plate. Standards and samples are pipetted into the wells and LIFR present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Human LIFR antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of LIFR bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.
Background/Introduction: LIFR, also known as CD118 (Cluster of Differentiation 118), is a subunit of a receptor for leukemia inhibitory factor. This gene encodes a protein that belongs to the type I cytokine receptor family. It is mapped to 5p31.1. The LIF receptor (LIFR) is the low-affinity binding chain that, together with the high-affinity converter subunit gp130, forms a high-affinity receptor complex that mediates the action of the leukemia-inhibitory factor. LIF is a polyfunctional cytokine that affects the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, togerther with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland.
Background/Introduction: LIFR, also known as CD118 (Cluster of Differentiation 118), is a subunit of a receptor for leukemia inhibitory factor. This gene encodes a protein that belongs to the type I cytokine receptor family. It is mapped to 5p31.1. The LIF receptor (LIFR) is the low-affinity binding chain that, together with the high-affinity converter subunit gp130, forms a high-affinity receptor complex that mediates the action of the leukemia-inhibitory factor. LIF is a polyfunctional cytokine that affects the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, togerther with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
– Da
NCBI Official Full Name
leukemia inhibitory factor receptor
NCBI Official Synonym Full Names
leukemia inhibitory factor receptor alpha
NCBI Official Symbol
LIFR
NCBI Official Synonym Symbols
SWS; SJS2; STWS; CD118; LIF-R
NCBI Protein Information
leukemia inhibitory factor receptor; LIF receptor; CD118 antigen
UniProt Protein Name
Leukemia inhibitory factor receptor
UniProt Gene Name
LIFR
UniProt Synonym Gene Names
LIF receptor; LIF-R
UniProt Entry Name
LIFR_HUMAN
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Product Notes
The Human LIFR lifr (Catalog #AAA106032) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA106032 ELISA Kit recognizes Human LIFR. AAA Biotech's LIFR can be used in a range of immunoassay formats including, but not limited to, ELISA (Sandwich ELISA). Researchers should empirically determine the suitability of the LIFR lifr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LIFR, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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