Standard Curve (Sample)
(Human LOX-1/OLR1 PicoKine ELISA Kit standard curve)
Human LOX-1/OLR1 ELISA Kit | OLR1 elisa kit
Human LOX-1/OLR1 PicoKine ELISA Kit
Gene Names
OLR1; LOX1; LOXIN; SLOX1; CLEC8A; SCARE1
Reactivity
Human
Synonyms
LOX-1/OLR1; N/A; Human LOX-1/OLR1 PicoKine ELISA Kit; Oxidized low-density lipoprotein receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; C-type lectin domain family 8 member A; CLEC8A; hLOX-1; Lectin-like oxidized LDL receptor 1; Lectin-like oxLDL receptor 1; Lectin-type oxidized LDL receptor 1; LOX-1; LOXIN; Olr1; OLR1_HUMAN; Ox-LDL receptor 1; Oxidized low density lipoprotein (lectin like) receptor 1; Oxidized low density lipoprotein receptor 1 soluble form; SCARE1; Scavenger receptor class E member 1; SLOX1; OLR1 elisa kit
Reactivity
Human
Specificity
Natural and recombinant human LOX-1
Sequence Length
273
Samples
Cell culture supernates, serum and plasma(heparin, EDTA).
Assay Type
Sandwich
Detection Range
31.2pg/ml-2000pg/ml
Sensitivity
< 10pg/ml
Intra-assay Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision.
Inter-assay Precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision.
Preparation and Storage
Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
Standard Curve (Sample)
(Human LOX-1/OLR1 PicoKine ELISA Kit standard curve)
Standard Curve (Sample)
(Human LOX-1/OLR1 PicoKine ELISA Kit standard curve)
Related Product Information for OLR1 elisa kit
Principle of the Assay: The human LOX-1 ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for LOX-1 has been precoated onto 96-well plates. Standards(NSO, S61-Q273) and test samples are added to the wells, a biotinylated detection polye!onal antibody from goat specific for LOX-1 is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the human LOX-1 amount of sample captured in plate.
Background: LOX-1 (lectin-type oxidized LDL receptor 1) also known as OLR 1, is a protein that in humans is encoded by the OLR1 gene. LOX-1 is a receptor protein which belongs to the C-type lectin superfamily. The LOX1 gene is mapped to 12p13-p12 by fluorescence in situ hybridization. LOX1 is expressed on the plasma membrane of differentiated macrophages, but not on monocytes. The LOX1 protein acts as a macrophage scavenger receptor. LOX1 expression was detected in all choroidal neovascular membranes, regardless of structure, whereas there was no evidence of LOX1 within the posterior segments of normal eyes. LOX1 plays an active role in the pathogenesis of choroidal neovascularization, especially in ARMD.
Background: LOX-1 (lectin-type oxidized LDL receptor 1) also known as OLR 1, is a protein that in humans is encoded by the OLR1 gene. LOX-1 is a receptor protein which belongs to the C-type lectin superfamily. The LOX1 gene is mapped to 12p13-p12 by fluorescence in situ hybridization. LOX1 is expressed on the plasma membrane of differentiated macrophages, but not on monocytes. The LOX1 protein acts as a macrophage scavenger receptor. LOX1 expression was detected in all choroidal neovascular membranes, regardless of structure, whereas there was no evidence of LOX1 within the posterior segments of normal eyes. LOX1 plays an active role in the pathogenesis of choroidal neovascularization, especially in ARMD.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
21,425 Da
NCBI Official Full Name
Oxidized low-density lipoprotein receptor 1
NCBI Official Synonym Full Names
oxidized low density lipoprotein (lectin-like) receptor 1
NCBI Official Symbol
OLR1
NCBI Official Synonym Symbols
LOX1; LOXIN; SLOX1; CLEC8A; SCARE1
NCBI Protein Information
oxidized low-density lipoprotein receptor 1; hLOX-1; ox LDL receptor 1; lectin-type oxidized LDL receptor 1; scavenger receptor class E, member 1; C-type lectin domain family 8 member A; oxidized low-density lipoprotein receptor 1, soluble form
UniProt Protein Name
Oxidized low-density lipoprotein receptor 1
UniProt Gene Name
OLR1
UniProt Synonym Gene Names
CLEC8A; LOX1; Ox-LDL receptor 1; LOX-1; Lectin-like oxLDL receptor 1; hLOX-1
UniProt Entry Name
OLR1_HUMAN
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Product Notes
The Human OLR1 olr1 (Catalog #AAA45548) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA45548 ELISA Kit recognizes Human OLR1. It is sometimes possible for the material contained within the vial of "LOX-1/OLR1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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