Human MBL2 ELISA Kit | MBL2 elisa kit

Human MBL2 Binding Protein ELISA Kit

Cat. Num. AAA261668

• Gene Names: MBL2; MBL; MBP; MBP1; MBPD; MBL2D; MBP-C; COLEC1; HSMBPC
• Reactivity: Human
• Applications: ELISA
• Synonyms: MBL2; N/A; Human MBL2 Binding Protein ELISA Kit; COLEC1; MBL; Mannose-binding protein C; MBP-C; Collectin-1; MBP1; Mannan-binding protein; Mannose-binding lectin; MBL2 elisa kit

• Reactivity: Human
• Specificity: The Human MBL2 Binding Protein ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human MBL2 Binding Protein proteins within the range of 312 pg/ml - 20000 pg/ml.
• Sequence Length: 248
• Samples: Cell Culture Supernatants, Serum, Plasma.
• Sensitivity: 10 pg/ml.

• Applicable Applications for MBL2 elisa kit: ELISA (Sandwich ELISA)
• Preparation and Storage: Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.

Standard Curve (Sample)

Related Product Information for MBL2 elisa kit

Principle of the Assay||The Human MBL2 Binding Protein ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human MBL2 Binding Protein in Cell Culture Supernatants, Serum, Plasma. This assay employs an antibody specific for Human MBL2 Binding Protein coated on a 96-well plate. Standards and samples are pipetted into the wells and MBL2 Binding Protein present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Human MBL2 Binding Protein antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of MBL2 Binding Protein bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.

Background/Introduction: MBL2, also called mannose-binding lectin (protein C) 2, soluble or Mannose-binding lectin (MBL) is a lectin that is instrumental in innate immunity. MBL2 is mapped to chromosome 10q11.2-q21. It belongs to the class of collectins in the C-type lectin superfamily, whose function appears to be pattern recognition in the first line of defense in the pre-immune host. MBL2 recognizes carbohydrate patterns, found on the surface of a large number of pathogenic micro-organisms, including bacteria, viruses, protozoa and fungi. Binding MBL2 to a micro-organism results in activation of the lectin pathway of the complement system. Another important function of MBL2 is that this molecule binds senescent and apoptotic cells and enhances engulfment of whole, intact apoptotic cells, as well as cell debris by phagocytes.

NCBI and Uniprot Product Information

• NCBI GI #: 126676
• NCBI GeneID: 4153
• UniProt Accession #: P11226; Q4VB12; Q4VB13; Q4VB14; Q5SQS3; Q86SI4; Q96KE4; Q96TF7; Q96TF8; Q96TF9
• Molecular Weight: 26,144 Da
• NCBI Official Full Name: Mannose-binding protein C
• NCBI Official Synonym Full Names: mannose binding lectin 2
• NCBI Official Symbol: MBL2
• NCBI Official Synonym Symbols: MBL; MBP; MBP1; MBPD; MBL2D; MBP-C; COLEC1; HSMBPC
• NCBI Protein Information: mannose-binding protein C
• UniProt Protein Name: Mannose-binding protein C
• UniProt Gene Name: MBL2
• UniProt Synonym Gene Names: COLEC1; MBL; MBP-C
• UniProt Entry Name: MBL2_HUMAN