Human Neurotrophic tyrosine kinase receptor type 2, NTRK2 ELISA Kit | NTRK2 elisa kit
Human Neurotrophic tyrosine kinase receptor type 2, NTRK2 Primacu ELISA Kit
Gene Names
NTRK2; TRKB; trk-B; GP145-TrkB
Reactivity
Human
Synonyms
Neurotrophic tyrosine kinase receptor type 2, NTRK2; N/A; Human Neurotrophic tyrosine kinase receptor type 2, NTRK2 Primacu ELISA Kit; BDNF/NT-3 growth factors receptor; TrkB; TRKB; NTRK2 elisa kit
Reactivity
Human
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
10.98-700pg/mL
Sensitivity
2.62pg/mL
Standard Solution
7ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C
Related Product Information for NTRK2 elisa kit
TrkB receptor also known as TrkB tyrosine kinase or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 (NTRK2) is a single transmembrane catalytic receptor with intracellular tyrosine kinase activity. TrkB/NTRK2 is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. TrkB tyrosine kinase (TrkB) or NTRK2 is coupled to the Ras, Cdc42/Rac/RhoG, MAPK, PI3-K, and PLCgamma signaling pathways. There are four members of the Trk family; TrkA, TrkB, and TrkC and a related p75NTR receptor. Each family member binds different neurotrophins with varying affinities. TrkB/NTRK has the highest affinity for brain-derived neurotrophic factor (BDNF) and is involved in neuronal plasticity, long-term potentiation, and apoptosis of CNS neurons. Other neurotrophins include nerve growth factor(NGF), neurotrophin-3 and neurotrophin-4. TrkB/NTRK is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signaling through this kinase leads to cell differentiation. Mutations in TrkB/NTRK have been associated with obesity and mood disorders. Cancer Immunotherapy Immune Checkpoint Immunotherapy Targeted Therapy
Product Categories/Family for NTRK2 elisa kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
91,999 Da
NCBI Official Full Name
BDNF/NT-3 growth factors receptor isoform b
NCBI Official Synonym Full Names
neurotrophic tyrosine kinase, receptor, type 2
NCBI Official Symbol
NTRK2
NCBI Official Synonym Symbols
TRKB; trk-B; GP145-TrkB
NCBI Protein Information
BDNF/NT-3 growth factors receptor; trkB tyrosine kinase; tyrosine kinase receptor B; tropomyosin-related kinase B; BDNF-tropomyosine receptor kinase B
UniProt Protein Name
BDNF/NT-3 growth factors receptor
UniProt Gene Name
NTRK2
UniProt Synonym Gene Names
TRKB; Trk-B
UniProt Entry Name
NTRK2_HUMAN
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Product Notes
The Human NTRK2 ntrk2 (Catalog #AAA124364) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124364 ELISA Kit recognizes Human NTRK2. It is sometimes possible for the material contained within the vial of "Neurotrophic tyrosine kinase receptor type 2, NTRK2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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