Standard Curve (Sample)
Human PAI-1 ELISA Kit | PAI-1 elisa kit
Human PAI-Pre-Coated ELISA Kit
Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Reactivity
Human
Synonyms
PAI-1; N/A; Human PAI-Pre-Coated ELISA Kit; PAI-1 elisa kit
Reactivity
Human
Specificity
Natural and recombinant Human PAI-1 Pre-Coated ELISA Kit
Assay Type
Solid Phase Sandwich ELISA: 96-Well Strip Plate
Detection Range
156pg/ml-10,000pg/ml
Sensitivity
<10pg/ml
Components
Anti-Human PAI-1 Pre-coated 96-well strip microplate
Human PAI-1 Standard
Human PAI-1 Biotinylated antibody (100x)
Avidin-Biotin-Peroxidase Complex (100x)
Sample Diluent
Antibody Diluent
Avidin-Biotin-Peroxidase Diluent
Wash Buffer Concentrate (Powder for 1000mL)
Color Developing Reagent
Stop Solution
Plate Sealers
Human PAI-1 Standard
Human PAI-1 Biotinylated antibody (100x)
Avidin-Biotin-Peroxidase Complex (100x)
Sample Diluent
Antibody Diluent
Avidin-Biotin-Peroxidase Diluent
Wash Buffer Concentrate (Powder for 1000mL)
Color Developing Reagent
Stop Solution
Plate Sealers
Interference
No detectable cross-reactivity with other relevant proteins
Preparation and Storage
Store the unopened product at 2-8 degree C.
Standard Curve (Sample)
Standard Curve (Sample)
Related Product Information for PAI-1 elisa kit
Plasminogen Activator Inhibitor-1 (PAI-1, Serpin E1) is a member of the serpin family of serine protease inhibitors, and is the primary inhibitor of urokinase and tissue plasminogen activator (tPA). PAI-1 is expressed predominantly in adipose, liver and vascular tissues, but is also produced by certain tumor cells. Elevated levels of PAI-1 are associated with obesity, diabetes and cardiovascular disease, and increased production of PAI-1 is induced by various obesity-related factors, such as TNFalpha, glucose, insulin, and very-low-density lipoprotein. The obesity-related elevation of PAI-1 levels, along with the consequential deficiency in plasminogen activators, can lead directly to increased risk of thrombosis and other coronary diseases. Accordingly, PAI-1 has been implicated as an important molecular link between obesity and coronary disease. PAI-1 can also specifically bind vitronectin (VTN) to form a stable active complex with an increased circulatory half-life relative to free PAI-1. Human PAI-1 Pre-Coated ELISA (Enzyme-Linked Immunosorbent Assay) kit is a solid phase immunoassay specially designed to measure PAI-1 with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for PAI-1. It contains sf21-expressed recombinant PAI-1. The detection antibody is a biotinylated goat polyclonal antibody specific for PAI-1. The kit is analytically validated with ready to use reagents.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
45,060 Da
NCBI Official Full Name
plasminogen activator inhibitor 1
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
NCBI Official Symbol
SERPINE1
NCBI Official Synonym Symbols
PAI; PAI1; PAI-1; PLANH1
NCBI Protein Information
plasminogen activator inhibitor 1; serpin E1; endothelial plasminogen activator inhibitor; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
UniProt Protein Name
Plasminogen activator inhibitor 1
UniProt Gene Name
SERPINE1
UniProt Synonym Gene Names
PAI1; PLANH1; PAI; PAI-1
UniProt Entry Name
PAI1_HUMAN
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Product Notes
The Human PAI-1 serpine1 (Catalog #AAA79365) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA79365 ELISA Kit recognizes Human PAI-1. It is sometimes possible for the material contained within the vial of "PAI-1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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