Application Data
(This assay recognizes both recombinant and natural Human PCSK9. The factors listed below were prepared at 300ng/mL in dilution buffer and assayed for cross-reactivity. No cross-reactivity was observed.)
Human PCSK9 ELISA Kit | PCSK9 elisa kit
Human PCSK9 ELISA Kit
Reactivity
Human
Synonyms
PCSK9; N/A; Human PCSK9 ELISA Kit; PCSK9 ELISA Kit, Human; proprotein convertase subtilisin/kexin type 9; FH3 ELISA Kit, Human; HCHOLA3 ELISA Kit, Human; LDLCQ1 ELISA Kit, Human; NARC-1 ELISA Kit, Human; NARC1 ELISA Kit, Human; PC9 ELISA Kit, Human; PCSK9 elisa kit
Reactivity
Human
Specificity
For the quantitative determination of Human PCSK9 concentration in serum and plasma.
Assay Type
Solid Phase Sandwich ELISA (quantitative)
Sample Types
Serum, Plasma
Detection Range
468.75-30000pg/mL
Sensitivity
132.17pg/mL
Conjugation
HRP
Interference
Preparations of human PCSK9 at 300ng/mL in a mid-range recombinant human PCSK9 control were assayed for interference. No significant interference was observed.
Materials Provided
1. 96 well microplate coated with Capture Antibody
2. Detection Antibody conjugated to HRP
3. Standards
4. Wash Buffer Concentrate
5. Dilution Buffer Concentrate
6. Color Reagent A
7. Color Reagent B
8. Stop Solution
2. Detection Antibody conjugated to HRP
3. Standards
4. Wash Buffer Concentrate
5. Dilution Buffer Concentrate
6. Color Reagent A
7. Color Reagent B
8. Stop Solution
Application Data
(This assay recognizes both recombinant and natural Human PCSK9. The factors listed below were prepared at 300ng/mL in dilution buffer and assayed for cross-reactivity. No cross-reactivity was observed.)
Application Data
(This assay recognizes both recombinant and natural Human PCSK9. The factors listed below were prepared at 300ng/mL in dilution buffer and assayed for cross-reactivity. No cross-reactivity was observed.)
Standard Curve (Sample)
(This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.)
Standard Curve (Sample)
(This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.)
Related Product Information for PCSK9 elisa kit
This PCSK9 ELISA Kit, Human is an enzyme-linked immunosorbent assay for the quantitative measurement of Human PCSK9 protein in Serum, Plasma. It contains recombinant Human PCSK9, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
Background: Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the secretory subtilase family. PCSK9 protein is an enzyme which in humans is encoded by the PCSK9 gene with orthologs found across many species. It is expressed in neuroepithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells. PCSK9 protein is highly expressed in the liver and regulates low density lipoprotein receptor (LDLR) protein levels. Inhibition of PCSK9 protein function is currently being explored as a means of lowering cholesterol levels. Thereby, PCSK9 protein is regarded as a new strategy to treat hypercholesterolemia. PCSK9 protein contributes to cholesterol homeostasis and may have a role in the differentiation of cortical neurons.
Background: Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the secretory subtilase family. PCSK9 protein is an enzyme which in humans is encoded by the PCSK9 gene with orthologs found across many species. It is expressed in neuroepithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells. PCSK9 protein is highly expressed in the liver and regulates low density lipoprotein receptor (LDLR) protein levels. Inhibition of PCSK9 protein function is currently being explored as a means of lowering cholesterol levels. Thereby, PCSK9 protein is regarded as a new strategy to treat hypercholesterolemia. PCSK9 protein contributes to cholesterol homeostasis and may have a role in the differentiation of cortical neurons.
References
Sseidah, N.G. et al., 2003, Proc. Natl. Acad. Sci. USA. 100: 928-933.Beyer, T.P. et al., 2007, J. Lipid.
Res. 48: 1488-1498Shan, L. et al., 2008, Biochem. Biophys. Res. Commun. 375: 69-73.Benjannet, S. et al., 2005, J. Biol. Chem. 279: 48865-48875.
Abifadel, M. et al., 2003, Nat. Genet. 34: 154-156.
Res. 48: 1488-1498Shan, L. et al., 2008, Biochem. Biophys. Res. Commun. 375: 69-73.Benjannet, S. et al., 2005, J. Biol. Chem. 279: 48865-48875.
Abifadel, M. et al., 2003, Nat. Genet. 34: 154-156.
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Product Notes
The Human PCSK9 (Catalog #AAA258373) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA258373 ELISA Kit recognizes Human PCSK9. It is sometimes possible for the material contained within the vial of "PCSK9, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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