Reactivity
Human
Specificity
Recognizes both natural and recombinant RANTES
Samples
Cell culture supernatant, serum and plasma
Detection Range
250-6.25pg/ml
Sensitivity
1.2pg/ml
Incubation
1h45
Sample Size
10 ul
Cross Reaction
No cross reactivity with other cytokines tested
Kit Content
ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents and a detailed procedure.
Related Product Information for RANTES elisa kit
CCL5, also known as Regulated upon Activation, Normal T Cell Expressed and Secreted (RANTES), is a member of the CC family of chemokine (Chemotactic cytokines that control the migration of immune cells in tissue). The mature form of the protein consists of 68 amino acids with a molecular mas of approx 8 kDa.
Mainly expressed by T-cells and monocytes and abundantly by epithelial cells, fibroblasts, and thrombocytes, it plays an active role in recruiting leucocytes into inflammatory sites through receptors CCR1, CCR3, CCR4 and CCR5 and inducing their proliferation and activation.
Described as the major HIV-1 co-receptor, it inhibits the virus entry and replication within cells at low concentration. The CCR5-CCL5 blockade maybe thus an effective strategy for HIV prevention.
RANTES is involved in transplantations (level is higher during rejection of renal transplant) and plays an important role in various human disorders, such as atherosclerosis, COVID-19, SARS, atopic dermatitis, asthma, glomerulonephritis, alcohol liver disease, acute liver failure and viral hepatitis. Increased level of RANTES was discovered in lots of cancer, hepatocellular carcinoma, stomach, prostate and pancreatic cancer).
Mainly expressed by T-cells and monocytes and abundantly by epithelial cells, fibroblasts, and thrombocytes, it plays an active role in recruiting leucocytes into inflammatory sites through receptors CCR1, CCR3, CCR4 and CCR5 and inducing their proliferation and activation.
Described as the major HIV-1 co-receptor, it inhibits the virus entry and replication within cells at low concentration. The CCR5-CCL5 blockade maybe thus an effective strategy for HIV prevention.
RANTES is involved in transplantations (level is higher during rejection of renal transplant) and plays an important role in various human disorders, such as atherosclerosis, COVID-19, SARS, atopic dermatitis, asthma, glomerulonephritis, alcohol liver disease, acute liver failure and viral hepatitis. Increased level of RANTES was discovered in lots of cancer, hepatocellular carcinoma, stomach, prostate and pancreatic cancer).
Product Categories/Family for RANTES elisa kit
Similar Products
Product Notes
The Human RANTES (Catalog #AAA58644) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA58644 ELISA Kit recognizes Human RANTES. It is sometimes possible for the material contained within the vial of "RANTES, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
