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product-image-AAA124316_SC15.jpg Standard Curve (Sample) (Typical Testing Data/Standard Curve (for reference only))

Human Receptor Tyrosine-Protein Kinase Erbb-3, ERBB3 ELISA Kit | ERBB3 elisa kit

Human Receptor Tyrosine-Protein Kinase Erbb-3, ERBB3 Primacu ELISA Kit

Gene Names
ERBB3; HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3
Reactivity
Human
Synonyms
Receptor Tyrosine-Protein Kinase Erbb-3, ERBB3; N/A; Human Receptor Tyrosine-Protein Kinase Erbb-3, ERBB3 Primacu ELISA Kit; Receptor tyrosine-protein kinase erbB-3; HER3; ERBB3 elisa kit
Ordering
Reactivity
Human
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
18.75-1200pg/mL
Sensitivity
4.36pg/mL
Standard Solution
12ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C

Standard Curve (Sample)

(Typical Testing Data/Standard Curve (for reference only))

product-image-AAA124316_SC15.jpg Standard Curve (Sample) (Typical Testing Data/Standard Curve (for reference only))
Related Product Information for ERBB3 elisa kit
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain., and therefore can not mediate the intracellular signal transduction through protein phosphorylation. However, its heterodimer with ErbB2 or other EGFR members responsible for tyrosine phosphorylation forms a receptor complex with high affinity, and initiates the related pathway which lead to cell proliferation or differentiation. ErbB3 has been shown to implicated in numerous cancers, including prostate, bladder, and breast tumors. This protein has different isoforms derived from alternative splicing variants, and among which, the secreted isoform lacking the intermembrane region modulates the activity of membrane-bound form. Cancer Immunotherapy Immune Checkpoint Immunotherapy Targeted Therapy
Product Categories/Family for ERBB3 elisa kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
148,098 Da
NCBI Official Full Name
receptor tyrosine-protein kinase erbB-3 isoform s
NCBI Official Synonym Full Names
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
NCBI Official Symbol
ERBB3
NCBI Official Synonym Symbols
HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3
NCBI Protein Information
receptor tyrosine-protein kinase erbB-3; proto-oncogene-like protein c-ErbB-3; tyrosine kinase-type cell surface receptor HER3
UniProt Protein Name
Receptor tyrosine-protein kinase erbB-3
UniProt Gene Name
ERBB3
UniProt Synonym Gene Names
HER3
UniProt Entry Name
ERBB3_HUMAN

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Product Notes

The Human ERBB3 erbb3 (Catalog #AAA124316) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124316 ELISA Kit recognizes Human ERBB3. It is sometimes possible for the material contained within the vial of "Receptor Tyrosine-Protein Kinase Erbb-3, ERBB3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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