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product-image-AAA331044_SC15.jpg Standard Curve (Sample)

Human Retinal-Specific ATP-Binding Cassette Transporter (ABCA4) ELISA Kit | ABCA4 elisa kit

Human Retinal-Specific ATP-Binding Cassette Transporter (ABCA4) ELISA Kit

Gene Names
ABCA4; FFM; RMP; ABCR; RP19; STGD; ABC10; ARMD2; CORD3; STGD1
Reactivity
Human
Synonyms
Retinal-Specific ATP-Binding Cassette Transporter (ABCA4); N/A; Human Retinal-Specific ATP-Binding Cassette Transporter (ABCA4) ELISA Kit; ABCA4; ABC10; ABCR; ARMD2; CORD3; DKFZp781N1972; FFM; FLJ17534; RMP; RP19; STGD; STGD1; ATP binding cassette transporter; ATP-binding cassette; sub-family A member 4; ATP-binding transporter; retina-specific; ABCA4 elisa kit
Ordering
Reactivity
Human
Specificity
Human Retinal-specific ATP-binding cassette transporter (ABCA4) ELISA Kit has high sensitivity and excellent specificity for detection of Human ABCA4. No significant cross-reactivity or interference between Human ABCA4 and analogues was observed.
Sequence Length
2273
Assay Type
Sandwich
Samples
Human serum, cell culture supernates and other biological fluids
Detection Range
15 ng/L - 240 ng/L
Sensitivity
< 1ng/L
Intra-assay Precision
Four samples of known concentration were tested twenty times on one plate to assess intra-assay precision. The CV (%)?9%.
Inter-assay Precision
Three samples of known concentration were tested in twenty separate assays to assess inter-assay precision. Assays were performed by at least three technicians using two lots of components. The CV (%)?11%.
Preparation and Storage
Store at 2-8 degree C.

Standard Curve (Sample)

product-image-AAA331044_SC15.jpg Standard Curve (Sample)
Related Product Information for ABCA4 elisa kit
Background: ABCA4 (ATP Binding Cassette Subfamily A Member 4) is a Protein Coding gene. Diseases associated with ABCA4 include Macular Degeneration, Age-Related, 2 and Cone-Rod Dystrophy 3. Among its related pathways are Diseases of the neuronal system and Regulation of activated PAK-2p34 by proteasome mediated degradation. Gene Ontology (GO) annotations related to this gene include transporter activity and ATPase-coupled transmembrane transporter activity. An important paralog of this gene is ABCA1.

Principle of the Assay: Human Retinal-specific ATP-binding cassette transporter (ABCA4) ELISA Kit employs a two-site sandwich ELISA to quantitate ABCA4 in samples. An antibody specific for ABCA4 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ABCA4 present is bound by the immobilized antibody. After removing any unbound substances, HRP-Conjugated Human ABCA4 detection antibody is added to the wells. Following a wash to remove any unbound HRP reagent, a Chromogen solution is added to the wells and color develops in proportion to the amount of ABCA4 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
24
UniProt Accession #
NCBI Official Full Name
Retinal-specific ATP-binding cassette transporter
NCBI Official Synonym Full Names
ATP binding cassette subfamily A member 4
NCBI Official Symbol
ABCA4
NCBI Official Synonym Symbols
FFM; RMP; ABCR; RP19; STGD; ABC10; ARMD2; CORD3; STGD1
NCBI Protein Information
retinal-specific ATP-binding cassette transporter
UniProt Protein Name
Retinal-specific ATP-binding cassette transporter
UniProt Gene Name
ABCA4
UniProt Synonym Gene Names
ABCR; RIM protein; RmP
UniProt Entry Name
ABCA4_HUMAN

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Product Notes

The Human ABCA4 abca4 (Catalog #AAA331044) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA331044 ELISA Kit recognizes Human ABCA4. It is sometimes possible for the material contained within the vial of "Retinal-Specific ATP-Binding Cassette Transporter (ABCA4), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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