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product-image-AAA330608_SC15.jpg Standard Curve (Sample)

Human Stereocilin (STRC) ELISA Kit | STRC elisa kit

Human Stereocilin (STRC) ELISA Kit

Gene Names
STRC; DFNB16
Reactivity
Human
Synonyms
Stereocilin (STRC); N/A; Human Stereocilin (STRC) ELISA Kit; STRC; DFNB16; MGC156147; STRC elisa kit
Ordering
Reactivity
Human
Specificity
Human Stereocilin (STRC) ELISA Kit has high sensitivity and excellent specificity for detection of Human STRC. No significant cross-reactivity or interference between Human STRC and analogues was observed.
Sequence Length
1775
Assay Type
Sandwich
Samples
Human serum, cell culture supernates and other biological fluids
Detection Range
25 ng/L - 400 ng/L
Sensitivity
< 1ng/L
Intra-assay Precision
Four samples of known concentration were tested twenty times on one plate to assess intra-assay precision. The CV (%)?9%.
Inter-assay Precision
Three samples of known concentration were tested in twenty separate assays to assess inter-assay precision. Assays were performed by at least three technicians using two lots of components. The CV (%)?11%.
Preparation and Storage
Store at 2-8 degree C.

Standard Curve (Sample)

product-image-AAA330608_SC15.jpg Standard Curve (Sample)
Related Product Information for STRC elisa kit
Background: Stereocilin is a protein that is associated with the hair bundle of the sensory hair cells in the inner ear. The hair bundle is composed of stiff microvilli called stereocilia and is involved with mechanoreception of sound waves. This gene is part of a tandem duplication on chromosome 15; the second copy is a pseudogene. Mutations in this gene cause autosomal recessive non-syndromic deafness. Defects in STRC are a cause of non-syndromic sensorineural deafness autosomal recessive type 16 (DFNB16). DFNB16 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.

Principle of the Assay: Human Stereocilin (STRC) ELISA Kit employs a two-site sandwich ELISA to quantitate STRC in samples. An antibody specific for STRC has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any STRC present is bound by the immobilized antibody. After removing any unbound substances, HRP-Conjugated Human STRC detection antibody is added to the wells. Following a wash to remove any unbound HRP reagent, a Chromogen solution is added to the wells and color develops in proportion to the amount of STRC bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
stereocilin
NCBI Official Synonym Full Names
stereocilin
NCBI Official Symbol
STRC
NCBI Official Synonym Symbols
DFNB16
NCBI Protein Information
stereocilin
UniProt Protein Name
Stereocilin
UniProt Gene Name
STRC
UniProt Entry Name
STRC_HUMAN

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Product Notes

The Human STRC strc (Catalog #AAA330608) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA330608 ELISA Kit recognizes Human STRC. It is sometimes possible for the material contained within the vial of "Stereocilin (STRC), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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