Standard Curve (Sample)
(Fig.1. Human Transforming growth factor beta receptor 2 (TGF-betaR2) Standard Curve.)
Human Transforming Growth Factor beta Receptor 2 (TGF-betaR2) ELISA Kit | TGF-betaR2 elisa kit
Human Transforming Growth Factor beta Receptor 2 (TGF-betaR2) ELISA Kit
Gene Names
TGFBR2; AAT3; FAA3; LDS2; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TBRII; TBR-ii; TGFR-2; TGFbeta-RII
Reactivity
Human
Synonyms
Transforming Growth Factor beta Receptor 2 (TGF-betaR2); N/A; Human Transforming Growth Factor beta Receptor 2 (TGF-betaR2) ELISA Kit; TGFBR2; AAT3; FAA3; LDS1B; LDS2B; MFS2; RIIC; TAAD2; TGFR-2; TGFbeta-RII; TGF-beta receptor typeB; TGF-beta type receptor; transforming growth factor beta receptor typeC; transforming growth factor; b; TGF-betaR2 elisa kit
Reactivity
Human
Specificity
Human Transforming growth factor beta receptor 2 (TGF-betaR2) ELISA Kit has high sensitivity and excellent specificity for detection of Human TGFBR2. No significant cross-reactivity or interference between Human TGFBR2 and analogues was observed.
Sequence Length
592
Assay Type
Sandwich ELISA (Quantitative)
Samples
Cell Culture Supernatants, Serum, Plasma, Other Biological Fluids
Detection Method
Colorimetric
Usage Notes
* Do not mix components from different kit lots or use reagents beyond the kit expiration date.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Preparation and Storage
Store at 2-8 degree C.
Standard Curve (Sample)
(Fig.1. Human Transforming growth factor beta receptor 2 (TGF-betaR2) Standard Curve.)
Standard Curve (Sample)
(Fig.1. Human Transforming growth factor beta receptor 2 (TGF-betaR2) Standard Curve.)
Related Product Information for TGF-betaR2 elisa kit
Description: This Human Transforming growth factor beta receptor 2 (TGF-betaR2) ELISA Kit employs a two-site sandwich ELISA to quantitate TGFBR2 in samples. An antibody specific for TGFBR2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any TGFBR2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TGFBR2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TGFBR2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background: Transforming growth factor beta receptor 2 (TGF-betaR2) is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. TGF-betaR2 is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in TGF-betaR2 have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.
Background: Transforming growth factor beta receptor 2 (TGF-betaR2) is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. TGF-betaR2 is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in TGF-betaR2 have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
TGF-beta receptor type-2 isoform A
NCBI Official Synonym Full Names
transforming growth factor beta receptor 2
NCBI Official Symbol
TGFBR2
NCBI Official Synonym Symbols
AAT3; FAA3; LDS2; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TBRII; TBR-ii; TGFR-2; TGFbeta-RII
NCBI Protein Information
TGF-beta receptor type-2
UniProt Protein Name
TGF-beta receptor type-2
UniProt Gene Name
TGFBR2
UniProt Synonym Gene Names
TGFR-2; TGF-beta receptor type II; TbetaR-II
UniProt Entry Name
TGFR2_HUMAN
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Product Notes
The Human TGF-betaR2 tgfbr2 (Catalog #AAA330726) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA330726 ELISA Kit recognizes Human TGF-betaR2. It is sometimes possible for the material contained within the vial of "Transforming Growth Factor beta Receptor 2 (TGF-betaR2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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