Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Human Tumor Necrosis Factor Receptor Superfamily Member 10A, TNFRSF10A ELISA Kit | TNFRSF10A elisa kit
Human Tumor Necrosis Factor Receptor Superfamily Member 10A, TNFRSF10A Primacu ELISA Kit
Gene Names
TNFRSF10A; DR4; APO2; CD261; TRAILR1; TRAILR-1
Reactivity
Human
Synonyms
Tumor Necrosis Factor Receptor Superfamily Member 10A, TNFRSF10A; N/A; Human Tumor Necrosis Factor Receptor Superfamily Member 10A, TNFRSF10A Primacu ELISA Kit; Tumor necrosis factor receptor superfamily member 10A; DR4; APO2; TRAILR1; TNFRSF10A elisa kit
Reactivity
Human
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
2.34-150pg/mL
Sensitivity
0.52pg/mL
Standard Solution
1.5ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C
Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Related Product Information for TNFRSF10A elisa kit
Tumor necrosis factor receptor superfamily, member 10a (TRAIL R1), also known as TRAIL receptor 1 (TRAIL R1) or CD261 antigen, is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. TRAIL R1/CD261/TNFRSF10A serves as a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. TRAIL R1 can promote the activation of NF-kappa-B. TRAIL R1/CD261/TNFRSF10A induces apoptosis of many transformed cell lines but not of normal tissues, even though its death domain-containing receptor, DR4, is expressed on both cell types. Cancer Immunotherapy Immune Checkpoint Immunotherapy Targeted Therapy
Product Categories/Family for TNFRSF10A elisa kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
50,089 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 10A
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 10a
NCBI Official Symbol
TNFRSF10A
NCBI Official Synonym Symbols
DR4; APO2; CD261; TRAILR1; TRAILR-1
NCBI Protein Information
tumor necrosis factor receptor superfamily member 10A; TRAIL-R1; TRAIL receptor 1; death receptor 4; cytotoxic TRAIL receptor; TNF-related apoptosis-inducing ligand receptor 1; tumor necrosis factor receptor superfamily member 10a variant 2
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 10A
UniProt Gene Name
TNFRSF10A
UniProt Synonym Gene Names
APO2; DR4; TRAILR1; TRAIL receptor 1; TRAIL-R1
UniProt Entry Name
TR10A_HUMAN
Similar Products
Product Notes
The Human TNFRSF10A tnfrsf10a (Catalog #AAA124452) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124452 ELISA Kit recognizes Human TNFRSF10A. It is sometimes possible for the material contained within the vial of "Tumor Necrosis Factor Receptor Superfamily Member 10A, TNFRSF10A, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.