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product-image-AAA76431_AD13.gif Application Data (Image: blots alpha-synuclein antibody on recombinant alpha-synuclein (left lane) and crude extract of mouse brain (right lane, courtesy Rogan Tinsley, Howard Florey Institute, University of Melbourne).)

a-synuclein Antibody | anti-SNCA antibody

a-synuclein, Monoclonal Antibody, Mouse

Gene Names
SNCA; PD1; NACP; PARK1; PARK4
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunofluorescence
Synonyms
a-synuclein; N/A; a-synuclein, Monoclonal Antibody, Mouse; anti-SNCA antibody
Ordering
Reactivity
Human, Mouse, Rat
Form/Format
Ascites Fluid - Liquid
Sequence Length
13
Applicable Applications for anti-SNCA antibody
WB (Western Blot), IF (Immunofluorescence)
Type Info
Mouse IgG

Application Data

(Image: blots alpha-synuclein antibody on recombinant alpha-synuclein (left lane) and crude extract of mouse brain (right lane, courtesy Rogan Tinsley, Howard Florey Institute, University of Melbourne).)

product-image-AAA76431_AD13.gif Application Data (Image: blots alpha-synuclein antibody on recombinant alpha-synuclein (left lane) and crude extract of mouse brain (right lane, courtesy Rogan Tinsley, Howard Florey Institute, University of Melbourne).)

Application Data

(Image: Mixed neuron-glial cultures stained with alpha-synuclein (red) and chicken polylclonal antibody to MAP2 (green). The alpha-synuclein antibody stains vesicular structures the perikarya and processes of the neurons in this Note that some of the neuronal perikarya contain much more alpha-synuclein than others. The blue channel shows the localization of DNA. Protocol on Data-sheet.)

product-image-AAA76431_AD15.gif Application Data (Image: Mixed neuron-glial cultures stained with alpha-synuclein (red) and chicken polylclonal antibody to MAP2 (green). The alpha-synuclein antibody stains vesicular structures the perikarya and processes of the neurons in this Note that some of the neuronal perikarya contain much more alpha-synuclein than others. The blue channel shows the localization of DNA. Protocol on Data-sheet.)
Related Product Information for anti-SNCA antibody
Note: This antibody will also bind human alpha-synuclein containing the A30P and A53T mutations.

Alpha synuclein is a member of the synuclein family, the other two proteins being beta and gamma synuclein. Alpha synuclein was originally isolated as a major synaptic vesicle associated protein from the electric organ of the fish Torpedo (1). Direct homologues of alpha-synuclein are found in all vertebrates. Later work connected alpha-synuclein with human brain pathology, when a protein originally identified as a component of NAC, the "Non-Amyloid beta Component of Alzheimer's disease amyloid" proved to be a peptide derived from alpha-synuclein (2).
Product Categories/Family for anti-SNCA antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
13,109 Da
NCBI Official Full Name
alpha synuclein, partial
NCBI Official Synonym Full Names
synuclein alpha
NCBI Official Symbol
SNCA
NCBI Official Synonym Symbols
PD1; NACP; PARK1; PARK4
NCBI Protein Information
alpha-synuclein
UniProt Protein Name
Alpha-synuclein
UniProt Gene Name
SNCA
UniProt Synonym Gene Names
NACP; PARK1; NACP
UniProt Entry Name
SYUA_HUMAN

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Product Notes

The SNCA snca (Catalog #AAA76431) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The a-synuclein, Monoclonal Antibody, Mouse reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's a-synuclein can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IF (Immunofluorescence). Researchers should empirically determine the suitability of the SNCA snca for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "a-synuclein, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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