VWF native protein
VWF protein
Gene Names
VWF; VWD; F8VWF
Purity
> 98% (by SDS-PAGE)
Synonyms
VWF; N/A; VWF protein; Von Willebrand Factor Protein; VWF native protein
Host
Human
Purity/Purification
> 98% (by SDS-PAGE)
Form/Format
Supplied as a liquid in 25mM Sodium Citrate, 100M Sodium Chloride, 100mM Glycine, pH 6.8.
No preservatives added.
No preservatives added.
Concentration
0.35 mg/ml (varies by lot)
Sequence Length
2813
Source
Prepared from Human serum/plasma
Protein Type
Native
Grade
Ultra Pure
Note
To thaw:
Place sample in a 37°C water bath. Allow sample to remain in water bath undisturbed for two minutes after disappearance of the last of frozen material. Remove sample from the water bath and mix by gentle agitation or gentle mixing with a pipette. If a percipitate is observed, continue to warm the sample in the 37°C water bath for an additional 2 to 3 minutes and mix again.
Place sample in a 37°C water bath. Allow sample to remain in water bath undisturbed for two minutes after disappearance of the last of frozen material. Remove sample from the water bath and mix by gentle agitation or gentle mixing with a pipette. If a percipitate is observed, continue to warm the sample in the 37°C water bath for an additional 2 to 3 minutes and mix again.
Biological Significance
Von Willebrand factor (vWF) is a multimeric plasma glycoprotein that is required for normal hemostatic platelet plug formation. The mature plasma protein is composed of apparently identical subunits (Mr=260,000) which are held together by disulfide bonds. The circulating vWF molecule ranges in size from dimers (Mr=520,000) to extremely large multimers (Mr>10,000,000). During normal hemostasis, the larger multimers of vWF are responsible for facilitating platelet plug formation by forming a bridge between platelet glycoprotein IB and exposed collagen in the subendothelium.
Biohazard Information
This product has been tested at serum donor level by FDA approved methods and found negative for HIV-1/2, HIV-1 antigen,STS, anti-HCV, anti-HBcore and anti-HTLV I & II and Hepatitis B surfave antigen. Since no test can offer complere assurance, handle with precaution.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Ships in dry ice. Upon receipt store at -70°C
Related Product Information for VWF native protein
Purified native Human VWF protein
Product Categories/Family for VWF native protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
260,000 daltons (monomer), 1-20x106 (multimers)
NCBI Official Full Name
von Willebrand factor
NCBI Official Synonym Full Names
von Willebrand factor
NCBI Official Symbol
VWF
NCBI Official Synonym Symbols
VWD; F8VWF
NCBI Protein Information
von Willebrand factor
UniProt Protein Name
von Willebrand factor
UniProt Gene Name
VWF
UniProt Synonym Gene Names
F8VWF; vWF
UniProt Entry Name
VWF_HUMAN
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Product Notes
The VWF vwf (Catalog #AAA75289) is a Native Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "VWF, Native Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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