Application Data
(Image: Blots of crude rat spinal cord homogenate blotted with MBP-Mouse Monoclonal Antibody. Protocol on data-sheet.)
anti-Human, Rat Myelin Basic Protein Antibody | anti-MBP antibody
Myelin Basic Protein, Monoclonal Antibody, Mouse
Reactivity
Human, Rat
Applications
Western Blot, Immunofluorescence
Synonyms
Myelin Basic Protein; N/A; Myelin Basic Protein, Monoclonal Antibody, Mouse; anti-MBP antibody
Reactivity
Human, Rat
Form/Format
Affinity Purified - Liquid
Sequence Length
304
Applicable Applications for anti-MBP antibody
WB (Western Blot), IF (Immunofluorescence)
Type Info
Chicken IgY
Immunogen
Mixture of 3 MBP peptides which are the different forms of the protein which are alternate transcription from a single gene.
Application Data
(Image: Blots of crude rat spinal cord homogenate blotted with MBP-Mouse Monoclonal Antibody. Protocol on data-sheet.)
Application Data
(Image: Blots of crude rat spinal cord homogenate blotted with MBP-Mouse Monoclonal Antibody. Protocol on data-sheet.)
Application Data
(Image: Shows rat mixed neuron/glial cultures stained with Myelin Basic Protein antibody (red), and also with chicken antibody to neurofilament NF-L (green). Blue is a DNA stain. Note that the MBP antibody stains an oligodendrocyte and some membrane shed from this cell. Other cells in the field include neurons, astrocytes, microglia and fibroblasts, all of which are completely negative for MBP, though the neuronal processes can be seen with the NF-L antibody. Protocol on data-sheet.)
Application Data
(Image: Shows rat mixed neuron/glial cultures stained with Myelin Basic Protein antibody (red), and also with chicken antibody to neurofilament NF-L (green). Blue is a DNA stain. Note that the MBP antibody stains an oligodendrocyte and some membrane shed from this cell. Other cells in the field include neurons, astrocytes, microglia and fibroblasts, all of which are completely negative for MBP, though the neuronal processes can be seen with the NF-L antibody. Protocol on data-sheet.)
Related Product Information for anti-MBP antibody
Myelin basic protein is reported to account for about 30 of the proteins in myelin found in the central nervous system. It can induce experimental allergic encephalomyelitis (EAE), a T-lymphocyte mediated disease due to delayed-type hypersensitivity; though each animal species appears to respond to a different fragment of the 170 amino acid polypeptide. Four different isoforms have been identified through cDNA cloning. All four of these variants are identical except for the insertion or deletion of two peptide fragments encoded by exons 2 and 5. Myelin basic protein is reported to be expressed in oligodendrocytes, myelin of white matter in the brain and spinal cord and in peripheral nerves, though it is expressed less abundantly in gray matter.
Product Categories/Family for anti-MBP antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
17,343 Da
NCBI Official Full Name
Myelin basic protein
NCBI Official Synonym Full Names
myelin basic protein
NCBI Official Symbol
MBP
NCBI Protein Information
Golli-MBP; myelin basic protein
UniProt Protein Name
Myelin basic protein
UniProt Gene Name
MBP
UniProt Synonym Gene Names
MBP
UniProt Entry Name
MBP_HUMAN
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Product Notes
The MBP mbp (Catalog #AAA76423) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Myelin Basic Protein, Monoclonal Antibody, Mouse reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Myelin Basic Protein can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IF (Immunofluorescence). Researchers should empirically determine the suitability of the MBP mbp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Myelin Basic Protein, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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