Application Data
(Recombinant Human IFN-alpha B2/IFNA8 was measured in a cell cytotoxicity assay using TF-1 cells. The ED<sub>50</sub> for this effect is 0.10?0.42 ng/mL, corresponding to a specific activity of 2.38×10<sup>6</sup>~1.0×10<sup>7</sup> units/mg.)
IFN-alpha B2/IFNA8 Recombinant Protein | IFNA8 recombinant protein
Recombinant Human IFN-alpha B2/IFNA8 Protein
Synonyms
IFN-alpha B2/IFNA8; N/A; Recombinant Human IFN-alpha B2/IFNA8 Protein; IFNA8; IFN-alpha 8; IFNalpha B2; IFN-alpha B2; IFN-alpha-8; IFN-alphaB; interferon alpha type 201; interferon alpha-8; Interferon alpha-B; interferon alpha-B'; Interferon alpha-B2; interferon, alpha 8; LeIF B; IFNA8 recombinant protein
Host
HEK293 cells
Form/Format
Lyophilized from a 0.22 um filtered solution of PBS, pH7.4.
Sequence
SLGCDLPQTHSLGNRRALILLAQMRRISPFSCLKDRHDFEFPQEEFDDKQFQKAQAISVLHEMIQQTFNLFSTKDSSAALDETLLDEFYIELDQQLNDLESCVMQEVGVIESPLMYEDSILAVRKYFQRITLYLTEKKYSSCAWEVVRAEIMRSFSLSINLQKRLKSKE
Species
Human
Tag
C-His
Endotoxin
<0.01EU/ug of the protein by LAL method.
Bio-Activity
Measured in a cell cytotoxicity assay using TF-1 cells. The ED50 for this effect is 0.10?0.42ng/mL, corresponding to a specific activity of 2.38×106~1.0×107 units/mg.
Preparation and Storage
Store at -20 degree C. Store the lyophilized protein at -20 degree C to -80 degree C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20 degree C for 3 months, at 2-8 degree C for up to 1 week.
After reconstitution, the protein solution is stable at -20 degree C for 3 months, at 2-8 degree C for up to 1 week.
Application Data
(Recombinant Human IFN-alpha B2/IFNA8 was measured in a cell cytotoxicity assay using TF-1 cells. The ED<sub>50</sub> for this effect is 0.10?0.42 ng/mL, corresponding to a specific activity of 2.38×10<sup>6</sup>~1.0×10<sup>7</sup> units/mg.)
Application Data
(Recombinant Human IFN-alpha B2/IFNA8 was measured in a cell cytotoxicity assay using TF-1 cells. The ED<sub>50</sub> for this effect is 0.10?0.42 ng/mL, corresponding to a specific activity of 2.38×10<sup>6</sup>~1.0×10<sup>7</sup> units/mg.)
SDS-PAGE
(Recombinant Human IFN-alpha B2/IFNA8 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 25-30 kDa.)
SDS-PAGE
(Recombinant Human IFN-alpha B2/IFNA8 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 25-30 kDa.)
Related Product Information for IFNA8 recombinant protein
Interferon alpha-B, also known as IFNA8, belongs to the alpha/beta interferon family. Interferons are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites, or tumor cells. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They also allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. Interferons also activate immune cells, such as natural killer cells and macrophages. They increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes. They also increase the ability of uninfected host cells to resist new infections by virus. Certain symptoms, such as aching muscles and fever, are related to the production of IFNs during infection. Produced by macrophages, IFN-alpha has antiviral activities.
Product Categories/Family for IFNA8 recombinant protein
NCBI and Uniprot Product Information
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Product Notes
The IFNA8 ifna8 (Catalog #AAA283397) is a Recombinant Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: SLGCDLPQTH SLGNRRALIL LAQMRRISPF SCLKDRHDFE FPQEEFDDKQ FQKAQAISVL HEMIQQTFNL FSTKDSSAAL DETLLDEFYI ELDQQLNDLE SCVMQEVGVI ESPLMYEDSI LAVRKYFQRI TLYLTEKKYS SCAWEVVRAE IMRSFSLSIN LQKRLKSKE. It is sometimes possible for the material contained within the vial of "IFN-alpha B2/IFNA8, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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