Ig gamma-1 chain C region Recombinant Protein | IGHG1 recombinant protein

Recombinant Human Ig gamma-1 chain C region

Cat. Num. AAA81659

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Ig gamma-1 chain C region; N/A; Recombinant Human Ig gamma-1 chain C region; IGHG1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-330aa; Full Length
• Sequence: ASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
• Sequence Length: 330

• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

Product Categories/Family for IGHG1 recombinant protein

Immunology

References

The nucleotide sequence of a human immunoglobulin C gamma1 gene.Ellison J.W., Berson B.J., Hood L.E.Nucleic Acids Res. 10:4071-4079(1982) The covalent structure of a human gamma G-immunoglobulin. VII. Amino acid sequence of heavy-chain cyanogen bromide fragments H1-H4.Cunningham B.A., Rutishauser U., Gall W.E., Gottlieb P.D., Waxdal M.J., Edelman G.M.Biochemistry 9:3161-3170(1970) The covalent structure of a human gamma G-immunoglobulin. 8. Amino acid sequence of heavy-chain cyanogen bromide fragments H5-H7.Rutishauser U., Cunningham B.A., Bennett C., Konigsberg W.H., Edelman G.M.Biochemistry 9:3171-3181(1970) The rule of antibody structure. The primary structure of a monoclonal IgG1 immunoglobulin (myeloma protein Nie) . III. The chymotryptic peptides of the H-chain, alignment of the tryptic peptides and discussion of the complete structure.Ponstingl H., Hilschmann N.Hoppe-Seyler's Z. Physiol. Chem. 357:1571-1604(1976) Three-dimensional structure determination of antibodies. Primary structure of crystallized monoclonal immunoglobulin IgG1 KOL, I.Schmidt W.E., Jung H.-D., Palm W., Hilschmann N.Hoppe-Seyler's Z. Physiol. Chem. 364:713-747(1983) The covalent structure of a human gamma G-immunoglobulin. X. Intrachain disulfide bonds.Gall W.E., Edelman G.M.Biochemistry 9:3188-3196(1970) Rule of antibody structure. The primary structure of a monoclonal IgG1 immunoglobulin (myeloma protein Nie) , I purification and characterization of the protein, the L- and H-chains, the cyanogen bromide cleavage products, and the disulfide bridges.Dreker L., Schwarz J., Reichel W., Hilschmann N.Hoppe-Seyler's Z. Physiol. Chem. 357:1515-1540(1976) Site-specific glycoprofiling of N-linked glycopeptides using MALDI-TOF MS strong correlation between signal strength and glycoform quantities.Thaysen-Andersen M., Mysling S., Hojrup P.Anal. Chem. 81:3933-3943(2009) Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.Chen R., Jiang X., Sun D., Han G., Wang F., Ye M., Wang L., Zou H.J. Proteome Res. 8:651-661(2009) A strategy for precise and large scale identification of core fucosylated glycoproteins.Jia W., Lu Z., Fu Y., Wang H.P., Wang L.H., Chi H., Yuan Z.F., Zheng Z.B., Song L.N., Han H.H., Liang Y.M., Wang J.L., Cai Y., Zhang Y.K., Deng Y.L., Ying W.T., He S.M., Qian X.H.Mol. Cell. Proteomics 8:913-923(2009) Initial characterization of the human central proteome.Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.BMC Syst. Biol. 5:17-17(2011) An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.J. Proteomics 96:253-262(2014) Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution.Deisenhofer J.Biochemistry 20:2361-2370(1981) Promiscuous translocations into immunoglobulin heavy chain switch regions in multiple myeloma.Bergsagel P.L., Chesi M., Nardini E., Brents L.A., Kirby S.L., Kuehl W.M.Proc. Natl. Acad. Sci. U.S.A. 93:13931-13936(1996) Translocations of 14q32 and deletions of 13q14 are common chromosomal abnormalities in systemic amyloidosis.Harrison C.J., Mazzullo H., Ross F.M., Cheung K.L., Gerrard G., Harewood L., Mehta A., Lachmann H.J., Hawkins P.N., Orchard K.H.Br. J. Haematol. 117:427-435(2002)

NCBI and Uniprot Product Information

• NCBI GI #: 121039
• NCBI GeneID: 3500
• UniProt Accession #: P01857
• Molecular Weight: 52.1 kDa
• NCBI Official Full Name: Ig gamma-1 chain C region
• NCBI Official Synonym Full Names: immunoglobulin heavy constant gamma 1 (G1m marker)
• NCBI Official Symbol: IGHG1
• UniProt Protein Name: Ig gamma-1 chain C region
• UniProt Gene Name: IGHG1
• UniProt Entry Name: IGHG1_HUMAN