Application Data
(Figure 2. ELISA plate pre-coated by 2 ug/mL (100 uL/well) Human IL15 Protein, hFc Tag (AAA47378) can bind Anti-IL15(ordesekimab biosimilar) mAb in a linear range of 3.20–400 ng/mL.)
IL15 recombinant protein
Human IL15 Protein, hFc Tag
Gene Names
IL15; IL-15
Purity
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Synonyms
IL15; N/A; Human IL15 Protein, hFc Tag; IL-15; Interleukin 15; MGC9721; OTTHUMP00000164617; IL15 recombinant protein
Host
HEK293 cells
Purity/Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Form/Format
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization.
Sequence
IL15 (Asn49-Ser162) + hFc (Glu99-Ala330)
Origin
Human
Reconstitution
Reconstitute with deionized water
Tag
C-Human Fc
Preparation and Storage
Store at -20 degree C to -80 degree C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80 degree C (Avoid repeated freezing and thawing).
Application Data
(Figure 2. ELISA plate pre-coated by 2 ug/mL (100 uL/well) Human IL15 Protein, hFc Tag (AAA47378) can bind Anti-IL15(ordesekimab biosimilar) mAb in a linear range of 3.20–400 ng/mL.)
Application Data
(Figure 2. ELISA plate pre-coated by 2 ug/mL (100 uL/well) Human IL15 Protein, hFc Tag (AAA47378) can bind Anti-IL15(ordesekimab biosimilar) mAb in a linear range of 3.20–400 ng/mL.)
SDS-PAGE
(Figure 1.Human IL15 Protein, hFc Tag on SDS-PAGE under reducing condition.)
SDS-PAGE
(Figure 1.Human IL15 Protein, hFc Tag on SDS-PAGE under reducing condition.)
Related Product Information for IL15 recombinant protein
The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x (L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011]
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
The protein has a predicted molecular mass of 38.9 kDa after removal of the signal peptide. The apparent molecular mass of IL15-hFc is approximately 35-55kDa due to glycosylation
NCBI Official Full Name
interleukin-15 isoform 1 preproprotein
NCBI Official Synonym Full Names
interleukin 15
NCBI Official Symbol
IL15
NCBI Official Synonym Symbols
IL-15
NCBI Protein Information
interleukin-15
UniProt Protein Name
Interleukin-15
UniProt Gene Name
IL15
UniProt Synonym Gene Names
IL-15
UniProt Entry Name
IL15_HUMAN
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Product Notes
The IL15 il15 (Catalog #AAA47378) is a Recombinant Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: IL15 (Asn49-Ser 162) + hFc (Glu99-Ala 330). It is sometimes possible for the material contained within the vial of "IL15, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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