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product-image-AAA263054_SC15.jpg Standard Curve (Sample)

Human IL-17RA ELISA Kit | IL17RA elisa kit

Human IL-17RA ELISA Kit

Gene Names
IL17RA; CD217; IL17R; IMD51; CANDF5; CDw217; IL-17RA; hIL-17R
Reactivity
Human
Synonyms
IL-17RA; N/A; Human IL-17RA ELISA Kit; IL17R; Interleukin-17 receptor A; IL-17 receptor A; CDw217; CD217; IL17RA elisa kit
Ordering
Reactivity
Human
Specificity
The Human IL-17RA ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human IL-17RA proteins within the range of 31.2 pg/ml - 2000 pg/ml.
Sequence Length
832
Samples
Cell Culture Supernates, Serum, Plasma
Sensitivity
<10 pg/ml
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.

Standard Curve (Sample)

product-image-AAA263054_SC15.jpg Standard Curve (Sample)
Related Product Information for IL17RA elisa kit
Principle of the Assay: The Human IL-17RA ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human IL-17RA in Cell Culture Supernates, Serum, Plasma. This assay employs an antibody specific for Human IL-17RA coated on a 96-well plate. Standards and samples are pipetted into the wells and IL-17RA present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Human IL-17RA antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of IL-17RA bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.

Background: Interleukin 17 receptor A, also known as IL17RA and CDw217 (cluster of differentiation w217), is a human gene. The IL17R gene is mapped to 22q11.22-q11.23 by radiation hybrid analysis. Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Also, it is showed that mouse Il17r bound HSV-13 and mouse Il17. Recombinant soluble Il17r inhibited mitogen-induced T-cell proliferation and Il2 production.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
92,153 Da
NCBI Official Full Name
interleukin-17 receptor A isoform 2
NCBI Official Synonym Full Names
interleukin 17 receptor A
NCBI Official Symbol
IL17RA
NCBI Official Synonym Symbols
CD217; IL17R; IMD51; CANDF5; CDw217; IL-17RA; hIL-17R
NCBI Protein Information
interleukin-17 receptor A
UniProt Protein Name
Interleukin-17 receptor A
UniProt Gene Name
IL17RA
UniProt Synonym Gene Names
IL17R; IL-17 receptor A; IL-17RA
UniProt Entry Name
I17RA_HUMAN

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Product Notes

The Human IL17RA il17ra (Catalog #AAA263054) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA263054 ELISA Kit recognizes Human IL17RA. It is sometimes possible for the material contained within the vial of "IL-17RA, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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