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IL-30 recombinant protein

Recombinant Human IL-30 protein (N-His)

Gene Names
IL27; p28; IL30; IL-27; IL27A; IL-27A; IL27p28
Purity
>98% as determined by reducing SDS-PAGE.
Synonyms
IL-30; N/A; Recombinant Human IL-30 protein (N-His); IL-27-p28 subunit; IL-30 recombinant protein
Ordering
Host
E Coli
Purity/Purification
>98% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from sterile PBS, pH 8.0
Sequence
Phe 29-Pro 243
Species
Human
Tag
N-His
Endotoxin
<0.1 EU per 1 ug of the protein by the LAL method.
Reconstitution
We recommend centrifuging the vial before opening to bring the contents to the bottom. Do not vortex.
It is recommended that reconstitution buffer be added to the vial to prepare a stock solution of 0.25 mg/mL. Concentration is measured by UV-Vis.
Preparation and Storage
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C.
Reconstituted protein solution can be stored at 4 to 8°C for 2 to 7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Related Product Information for IL-30 recombinant protein
IL-30, also known as IL-27A,p28. IL-27 protein is a member of the IL-6 superfamily, which is expressed on monocytes, endothelial cells, and dendritic cells. IL-27 protein is also referred to as the IL-12 p35-related protein, p28, is one subunit of a heterodimeric cytokine complex, and associates with another subunit EBI3 (EBV-induced gene 3), and IL-12 p40-related protein (IL-27B). IL-27 protein is an early product of activated antigen-presenting cells and drives the rapid clonal expansion of naive CD4(+) T cells and plays a role in the early regulation of Th1 cells initiation which drives efficient adaptive immune response. IL-27 protein has an antiproliferative activity on melanomas through WSX-1/STAT1 signaling. Thus, IL-27 protein may be an attractive candidate as an antitumor agent applicable to cancer immunotherapy.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
25.5 kDa
NCBI Official Full Name
Interleukin-27 subunit alpha
NCBI Official Synonym Full Names
interleukin 27
NCBI Official Symbol
IL27
NCBI Official Synonym Symbols
p28; IL30; IL-27; IL27A; IL-27A; IL27p28
NCBI Protein Information
interleukin-27 subunit alpha; IL27-A; IL-27-A; interleukin 30; interleukin-30; IL-27 p28 subunit; IL-27 subunit alpha
UniProt Protein Name
Interleukin-27 subunit alpha
UniProt Gene Name
IL27
UniProt Synonym Gene Names
IL27A; IL30; IL-27 subunit alpha; IL-27-A; IL27-A
UniProt Entry Name
IL27A_HUMAN

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Product Notes

The IL-30 il27 (Catalog #AAA178003) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Phe 29-Pro 243. It is sometimes possible for the material contained within the vial of "IL-30, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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