Application Data
(Measured by its ability to inhibit proliferation of MPC-11 cells. The ED<sub>50</sub> for this effect is 3.215-12.86 ng/mL, corresponding to a specific activity of 7.78×10<sup>4</sup>~3.11×10<sup>5</sup> units/mg.)
Activin A/INHBA Recombinant Protein | INHBA recombinant protein
Recombinant Human/Mouse/Rat mature Activin A/INHBA Protein
Synonyms
Activin A/INHBA; N/A; Recombinant Human/Mouse/Rat mature Activin A/INHBA Protein; EDF; FRP; INHBA; Activin A; INHBA recombinant protein
Host
CHO Cells
Form/Format
Lyophilized from a 0.22 um filtered solution of PBS, pH7.4.
Sequence
GLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
Species
Human
Endotoxin
<0.01 EU/ug of the protein by LAL method.
Bio-Activity
Measured by its ability to inhibit proliferation of MPC-11 cells. The ED50 for this effect is 3.215-12.86ng/mL, corresponding to a specific activity of 7.78×104~3.11×105 units/mg.
Preparation and Storage
Store at -20 degree C. Store the lyophilized protein at -20 degree C to -80 degree C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20 degree C for 3 months, at 2-8 degree C for up to 1 week.
After reconstitution, the protein solution is stable at -20 degree C for 3 months, at 2-8 degree C for up to 1 week.
Application Data
(Measured by its ability to inhibit proliferation of MPC-11 cells. The ED<sub>50</sub> for this effect is 3.215-12.86 ng/mL, corresponding to a specific activity of 7.78×10<sup>4</sup>~3.11×10<sup>5</sup> units/mg.)
Application Data
(Measured by its ability to inhibit proliferation of MPC-11 cells. The ED<sub>50</sub> for this effect is 3.215-12.86 ng/mL, corresponding to a specific activity of 7.78×10<sup>4</sup>~3.11×10<sup>5</sup> units/mg.)
SDS-PAGE
(Recombinant Human/Mouse/Rat mature Activin A/INHBA Protein was resolved with SDS PAGE under reducing (R) and non-reducing (NR) conditions ?showing single bands at 15-20 kDa and 25-30 kDa, respectively.)
SDS-PAGE
(Recombinant Human/Mouse/Rat mature Activin A/INHBA Protein was resolved with SDS PAGE under reducing (R) and non-reducing (NR) conditions ?showing single bands at 15-20 kDa and 25-30 kDa, respectively.)
Related Product Information for INHBA recombinant protein
The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.
Product Categories/Family for INHBA recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Protein Name
Inhibin beta A chain
UniProt Gene Name
INHBA
UniProt Synonym Gene Names
EDF
UniProt Entry Name
INHBA_HUMAN
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Product Notes
The INHBA inhba (Catalog #AAA283366) is a Recombinant Protein produced from CHO Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS. It is sometimes possible for the material contained within the vial of "Activin A/INHBA, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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