IL-23 active protein
Human IL-23
Gene Names
IL23A; P19; SGRF; IL-23; IL-23A; IL23P19
Reactivity
Human
Purity
> 95% by SDS-PAGE & HPLC analyses
Synonyms
IL-23; N/A; Human IL-23; IL-23 active protein
Host
Insect Cells
Reactivity
Human
Purity/Purification
> 95% by SDS-PAGE & HPLC analyses
Form/Format
Lyophilized
Sequence
RAVPGGSSPA WTQCQQLSQK LCTLAWSAHP LVGHMDLREE GDEETT NDVP HIQCGDGCDP QGLRDNSQFC LQRIHQGLIF YEKLLGSDIF T GEPSLLPDS PVGQLHASLL GLSQLLQPEG HHWETQQIPS LSPSQPW QRL LLRFKILRSL QAFVAVAARV FAHGAATLSP IWELKKDVYV VE LDWYPDAP GEMVVLTCDT PEEDGITWTL DQSSEVLGSG KTLTIQVK EF GDAGQYTCHK GGEVLSHSLL LLHKKEDGIW STDILKDQKE PKN KTFLRCE AKNYSGRFTC WWLTTISTDL TFSVKSSRGS SDPQGVTCG A ATLSAERVRG DNKEYEYSVE CQEDSACPAA EESLPIEVMV DAVH KLKYEN YTSSFFIRDI IKPDPPKNLQ LKPLKNSRQV EVSWEYPDTW STPHSYFSLT FCVQVQGKSK REKKDRVFTD KTSATVICRK NASIS VRAQD RYYSSSWSEW ASVPCS
Sequence Length
189
Biological Activity
Measured by its ability to induce IL-17 secretion by mouse splenocytes.
Preparation and Storage
Reconstitution: Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be sotred at 2-8 degree C. for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20 degree C to -80 degree C.
Storage/Stability: The lyophilized protein is stable at room temperature for up to 1 month. Working aliquots stored with a carrier protein are stable for at least 3 months at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Storage/Stability: The lyophilized protein is stable at room temperature for up to 1 month. Working aliquots stored with a carrier protein are stable for at least 3 months at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Related Product Information for IL-23 active protein
IL-23 is a proinflammatory heterodimeric protein composed of two subunits, a unique p19 subunit and a p40 subunit, which is shared with IL-12. IL-23 is secreted by activated dendritic cells and macrophages, and signals though a receptor comprised of IL-23R complexed with IL-12Rbeta2. IL-23 has been shown to enhance proliferation of memory T cells. It also stimulates the production of IFN-gamma in NK cells, induces IL-17 production, and drives Th17 mediated responses. Recombinant IL-23 is a 53.5 kDa heterodimeric protein consisting of two subunits, p19 (170 amino acids) and p40 (306 amino acids
Product Categories/Family for IL-23 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
20,730 Da
NCBI Official Full Name
interleukin-23 subunit alpha
NCBI Official Synonym Full Names
interleukin 23, alpha subunit p19
NCBI Official Symbol
IL23A
NCBI Official Synonym Symbols
P19; SGRF; IL-23; IL-23A; IL23P19
NCBI Protein Information
interleukin-23 subunit alpha; IL-23-A; IL-23p19; IL-23 subunit alpha; interleukin 23 p19 subunit; interleukin-23 subunit p19; JKA3 induced upon T-cell activation; interleukin-six, G-CSF related factor
UniProt Protein Name
Interleukin-23 subunit alpha
UniProt Gene Name
IL23A
UniProt Synonym Gene Names
SGRF; IL-23 subunit alpha; IL-23-A; IL-23p19
UniProt Entry Name
IL23A_HUMAN
Similar Products
Product Notes
The IL-23 il23a (Catalog #AAA79249) is an Active Protein produced from Insect Cells and is intended for research purposes only. The product is available for immediate purchase. The Human IL-23 reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: RAVPGGSSPA WTQCQQLSQK LCTLAWSAHP LVGHMDLREE GDEETT NDVP HIQCGDGCDP QGLRDNSQFC LQRIHQGLIF YEKLLGSDIF T GEPSLLPDS PVGQLHASLL GLSQLLQPEG HHWETQQIPS LSPSQPW QRL LLRFKILRSL QAFVAVAARV FAHGAATLSP IWELKKDVYV VE LDWYPDAP GEMVVLTCDT PEEDGITWTL DQSSEVLGSG KTLTIQVK EF GDAGQYTCHK GGEVLSHSLL LLHKKEDGIW STDILKDQKE PKN KTFLRCE AKNYSGRFTC WWLTTISTDL TFSVKSSRGS SDPQGVTCG An ATLSAERVRG DNKEYEYSVE CQEDSACPAA EESLPIEVMV DAVH KLKYEN YTSSFFIRDI IKPDPPKNLQ LKPLKNSRQV EVSWEYPDTW STPHSYFSLT FCVQVQGKSK REKKDRVFTD KTSATVICRK NASIS VRAQD RYYSSSWSEW ASVPCS. It is sometimes possible for the material contained within the vial of "IL-23, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.