WB (Western Blot)
(Recombinant KAT6A / MOZ (488-778) protein activity assay 0.5 ug Histone H3.1 was incubated with 0 ug (-), 0.1 ug (+), 0.2 ug (++), 0.4 ug (+++) KAT6A / MOZ (488-778) protein in a 20 ul reaction system containing 50 mM Tris-HCl pH 8.6, 2 mM MgCl2, 1 mM TCEP, 0.02% Triton X-100 and 20 uM Acetyl-CoA for 2 hr at RT. Reaction products were detected by Western blot using H3 pan-acetyl antibody .)
KAT6A/MOZ recombinant protein
Recombinant KAT6A/MOZ (488-778) protein
Gene Names
KAT6A; MOZ; MYST3; ZNF220; RUNXBP2; ZC2HC6A
Synonyms
KAT6A/MOZ; N/A; Recombinant KAT6A/MOZ (488-778) protein; KAT6A; MYST3; KAT6A/MOZ recombinant protein
Host
Baculovirus
Form/Format
Recombinant KAT6A/MOZ (488-778) protein is supplied in 25mM HEPES-NaOH pH7.5, 300mM NaCl, 10% glycerol, 0.04% Triton X-100, and 0.5mM TCEP.
Protein Species
Human
Tag
DYKDDDDK-Tag
Notes
This product was manufactured as described in Protein Details. Where possible, We has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for a given product is shown on the lot-specific Technical Data Sheet.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Shipping Temp: Dry Ice
Shipping Temp: Dry Ice
WB (Western Blot)
(Recombinant KAT6A / MOZ (488-778) protein activity assay 0.5 ug Histone H3.1 was incubated with 0 ug (-), 0.1 ug (+), 0.2 ug (++), 0.4 ug (+++) KAT6A / MOZ (488-778) protein in a 20 ul reaction system containing 50 mM Tris-HCl pH 8.6, 2 mM MgCl2, 1 mM TCEP, 0.02% Triton X-100 and 20 uM Acetyl-CoA for 2 hr at RT. Reaction products were detected by Western blot using H3 pan-acetyl antibody .)
WB (Western Blot)
(Recombinant KAT6A / MOZ (488-778) protein activity assay 0.5 ug Histone H3.1 was incubated with 0 ug (-), 0.1 ug (+), 0.2 ug (++), 0.4 ug (+++) KAT6A / MOZ (488-778) protein in a 20 ul reaction system containing 50 mM Tris-HCl pH 8.6, 2 mM MgCl2, 1 mM TCEP, 0.02% Triton X-100 and 20 uM Acetyl-CoA for 2 hr at RT. Reaction products were detected by Western blot using H3 pan-acetyl antibody .)
SDS-PAGE
(Recombinant KAT6A / MOZ (488-778) protein gel 10% SDS-PAGE gel with Coomassie staining MW: 35.5 kDa Purity: > 95%)
SDS-PAGE
(Recombinant KAT6A / MOZ (488-778) protein gel 10% SDS-PAGE gel with Coomassie staining MW: 35.5 kDa Purity: > 95%)
Related Product Information for KAT6A/MOZ recombinant protein
Short Description: KAT6A (Lysine Acetyltransferase 6A), also called as MOZ, MYST3 or ZNF220, is a histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). It is a component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. KAT6A may act as a transcriptional coactivator for RUNX1 and RUNX2. It also acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML. This protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain.
Background: KAT6A (Lysine Acetyltransferase 6A), also called as MOZ, MYST3 or ZNF220, is a histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). It is a component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. KAT6A may act as a transcriptional coactivator for RUNX1 and RUNX2. It also acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML. This protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain.
Background: KAT6A (Lysine Acetyltransferase 6A), also called as MOZ, MYST3 or ZNF220, is a histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). It is a component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. KAT6A may act as a transcriptional coactivator for RUNX1 and RUNX2. It also acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML. This protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain.
Product Categories/Family for KAT6A/MOZ recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
225,028 Da
NCBI Official Full Name
histone acetyltransferase KAT6A
NCBI Official Synonym Full Names
K(lysine) acetyltransferase 6A
NCBI Official Symbol
KAT6A
NCBI Official Synonym Symbols
MOZ; MYST3; ZNF220; RUNXBP2; ZC2HC6A
NCBI Protein Information
histone acetyltransferase KAT6A; MYST-3; zinc finger protein 220; histone acetyltransferase MYST3; Monocytic leukemia zinc finger protein; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3; runt-related transcription factor binding protein 2; runt-related transcri
UniProt Protein Name
Histone acetyltransferase KAT6A
UniProt Gene Name
KAT6A
UniProt Synonym Gene Names
MOZ; MYST3; RUNXBP2; ZNF220; MYST-3
UniProt Entry Name
KAT6A_HUMAN
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Product Notes
The KAT6A/MOZ kat6a (Catalog #AAA60180) is a Recombinant Protein produced from Baculovirus and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "KAT6A/MOZ, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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