Application Data
KAT6B recombinant protein
KAT6B (MYST4), Active
Gene Names
KAT6B; qkf; MORF; MOZ2; GTPTS; MYST4; ZC2HC6B; querkopf
Synonyms
KAT6B; N/A; KAT6B (MYST4), Active; KAT6B recombinant protein
Host
Sf9 insect cells using baculovirus
Form/Format
50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Sequence Positions
431-end
Sequence Length
8509
Species
Human
Tag
GST tag
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store product at -70 degree C.
For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature.
For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature.
For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Application Data
Application Data
Application Data
Application Data
Related Product Information for KAT6B recombinant protein
Description: Recombinant human KAT6B (MYST4) (431-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Scientific Background: KAT6B is the catalytic subunit of the histone acetyltransferase (HAT) elongator complex, which is ubiquitously expressed in adult human tissues. KAT6B is a 1,781aa-residue protein that contains a strong transcriptional repression domain at its N terminus and a highly potent activation domain at its C terminus (1). These domains of KAT6B may be involved in both positive and negative regulation of transcription and also involved in cerebral cortex development. KAT6B is important for cellular aging, proliferation, positive and negative transcriptional regulation and DNA damage repair (2).
Scientific Background: KAT6B is the catalytic subunit of the histone acetyltransferase (HAT) elongator complex, which is ubiquitously expressed in adult human tissues. KAT6B is a 1,781aa-residue protein that contains a strong transcriptional repression domain at its N terminus and a highly potent activation domain at its C terminus (1). These domains of KAT6B may be involved in both positive and negative regulation of transcription and also involved in cerebral cortex development. KAT6B is important for cellular aging, proliferation, positive and negative transcriptional regulation and DNA damage repair (2).
Product Categories/Family for KAT6B recombinant protein
References
1. Champagne, N. et.al: Identification of a human histone acetyltransferase related to monocytic leukemia zinc finger protein. J. Biol. Chem. 274: 28528-28536, 1999. 2. Pena AN, et.al: The role of the MORF/MRG family of genes in cell growth, differentiation, DNA repair, and thereby aging. DOI: 10.1196/annals: 299 -305, April 2007.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
~76 kDa
NCBI Official Full Name
Homo sapiens lysine acetyltransferase 6B (KAT6B), transcript variant 1, mRNA
NCBI Official Synonym Full Names
lysine acetyltransferase 6B
NCBI Official Symbol
KAT6B
NCBI Official Synonym Symbols
qkf; MORF; MOZ2; GTPTS; MYST4; ZC2HC6B; querkopf
NCBI Protein Information
histone acetyltransferase KAT6B
UniProt Protein Name
Histone acetyltransferase KAT6B
UniProt Gene Name
KAT6B
UniProt Synonym Gene Names
KIAA0383; MORF; MOZ2; MYST4; MYST-4
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Product Notes
The KAT6B kat6b (Catalog #AAA72999) is a Recombinant Protein produced from Sf9 insect cells using baculovirus and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 431-end. It is sometimes possible for the material contained within the vial of "KAT6B, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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