Voltage-gated potassium channel subunit beta-2 Recombinant Protein | KCNAB2 recombinant protein

Recombinant Human Voltage-gated potassium channel subunit beta-2

Cat. Num. AAA114255

• Gene Names: KCNAB2; AKR6A5; KCNA2B; HKvbeta2; KV-BETA-2; HKvbeta2.1; HKvbeta2.2
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Voltage-gated potassium channel subunit beta-2; N/A; Recombinant Human Voltage-gated potassium channel subunit beta-2; K(+) channel subunit beta-2; Kv-beta-2; hKvbeta2; KCNAB2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-367aa; Full Length
• Sequence: MYPESTTGSPARLSLRQTGSPGMIYSTRYGSPKRQLQFYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNADQLMENIGAIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS
• Sequence Length: 367

• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

Related Product Information for KCNAB2 recombinant protein

Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability. Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity. Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore. Promotes KCNA4 channel closure. Modulates the functional properties of KCNA5. Enhances KCNB2 channel activity. Binds NADPH and has NADPH-dependent aldoketoreductase activity. Has broad substrate specificity and can catalyze the reduction of methylglyoxal, 9,10-phenanthrenequinone, prostaglandin J2, 4-nitrobenzaldehyde, 4-nitroacetophenone and 4-oxo-trans-2-nonenal (in vitro).

Product Categories/Family for KCNAB2 recombinant protein

Neuroscience

References

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NCBI and Uniprot Product Information

• NCBI GI #: 315434245
• NCBI GeneID: 8514
• NCBI Accession #: NP_001186789.1
• NCBI GenBank Nucleotide #: NM_001199860.1
• UniProt Accession #: Q13303; O43659; Q2YD85; Q5TG82; Q5TG83; Q6ZNE4; Q99411; A0AVM9; A8K1A4; B0AZR7
• Molecular Weight: 57 kDa
• NCBI Official Full Name: voltage-gated potassium channel subunit beta-2 isoform 1
• NCBI Official Synonym Full Names: potassium voltage-gated channel subfamily A regulatory beta subunit 2
• NCBI Official Symbol: KCNAB2
• NCBI Official Synonym Symbols: AKR6A5; KCNA2B; HKvbeta2; KV-BETA-2; HKvbeta2.1; HKvbeta2.2
• NCBI Protein Information: voltage-gated potassium channel subunit beta-2
• UniProt Protein Name: Voltage-gated potassium channel subunit beta-2
• UniProt Gene Name: KCNAB2
• UniProt Synonym Gene Names: KCNA2B; KCNK2; hKvbeta2
• UniProt Entry Name: KCAB2_HUMAN