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SDS-PAGE

Lys-gingipain Recombinant Protein | kgp recombinant protein

Recombinant Porphyromonas gingivalis Lys-gingipain (kgp), partial

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Lys-gingipain; N/A; Recombinant Porphyromonas gingivalis Lys-gingipain (kgp), partial; Lysine-specific cysteine proteinase Kgp; kgp recombinant protein
Ordering
 
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For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
229-594aa; partial
Sequence
DVYTDHGDLYNTPVRMLVVAGAKFKEALKPWLTWKAQKGFYLDVHYTDEAEVGTTNASIKAFIHKKYNDGLAASAAPVFLALVGDTDVISGEKGKKTKKVTDLYYSAVDGDYFPEMYTFRMSASSPEELTNIIDKVLMYEKATMPDKSYLEKALLIAGADSYWNPKIGQQTIKYAVQYYYNQDHGYTDVYSYPKAPYTGCYSHLNTGVGFANYTAHGSETSWADPSLTATQVKALTNKDKYFLAIGNCCVTAQFDYPQPCFGEVMTRVKEKGAYAYIGSSPNSYWGEDYYWSVGANAVFGVQPTFEGTSMGSYDATFLEDSYNTVNSIMWAGNLAATHAGNIGNITHIGAHYYWEAYHVLGDGSVM
Species
Porphyromonas gingivalis (strain # 33277 / DSM 20709 / JCM 12257)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

Related Product Information for kgp recombinant protein
Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P. gingivalis with other oral bacteria.
References
"Biochemical and functional properties of lysine-specific cysteine proteinase (Lys-gingipain) as a virulence factor of Porphyromonas gingivalis in periodontal disease." Abe N., Kadowaki T., Okamoto K., Nakayama K., Ohishi M., Yamamoto K. J. Biochem. 123:305-312(1998)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
56.6 kDa
NCBI Official Full Name
lysine-specific cysteine proteinase Kgp
NCBI Official Symbol
kgp
NCBI Protein Information
lysine-specific cysteine proteinase Kgp
UniProt Protein Name
Lys-gingipain
UniProt Gene Name
kgp
UniProt Entry Name
KGP_PORG3

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Product Notes

The kgp kgp (Catalog #AAA18541) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 229-594aa; partial. The amino acid sequence is listed below: DVYTDHGDLY NTPVRMLVVA GAKFKEALKP WLTWKAQKGF YLDVHYTDEA EVGTTNASIK AFIHKKYNDG LAASAAPVFL ALVGDTDVIS GEKGKKTKKV TDLYYSAVDG DYFPEMYTFR MSASSPEELT NIIDKVLMYE KATMPDKSYL EKALLIAGAD SYWNPKIGQQ TIKYAVQYYY NQDHGYTDVY SYPKAPYTGC YSHLNTGVGF ANYTAHGSET SWADPSLTAT QVKALTNKDK YFLAIGNCCV TAQFDYPQPC FGEVMTRVKE KGAYAYIGSS PNSYWGEDYY WSVGANAVFG VQPTFEGTSM GSYDATFLED SYNTVNSIMW AGNLAATHAG NIGNITHIGA HYYWEAYHVL GDGSVM . It is sometimes possible for the material contained within the vial of "Lys-gingipain, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.