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Lactate Dehydrogenase Active Protein | LAD active protein

Lactate Dehydrogenase (LDH), Bovine Heart

Purity
Purified
Synonyms
Lactate Dehydrogenase; N/A; Lactate Dehydrogenase (LDH), Bovine Heart; LD; L-LDH; (S)-Lactate; LDH; Lactate Dehydrogenase (LDH), Bovine - Lyophilized; LAD active protein
Ordering
Purity/Purification
Purified
Form/Format
Lyophilized from 50 mM sodium phosphate, pH 7.4
Appearance: White to off-white powder
Sequence Length
331
Source
Bovine Heart
EC Number
1.1.1.27
Unit Definition
One unit will catalyze the oxidation of one micromole of L-lactate to pyruvate with simultaneous reduction of NAD+ to NADH per minute at 37°C and pH 9.4.
Specific Activity
240 U/mg protein (Coomassie)
Solubility
Clear, colorless to tan solution with possible fine particulates
Reconstitution
Clear and colorless in 10 mg/mL saline
Recertification
3 years
Protein
5.4 U/vial (Coomassie)
Contaminants
AST/GOT: <=0.6%, ALT/GPT: <=0.07%, Pyruvate Kinase: Typically <=0.1%, Ammonia: <=0.1 micromole/mg
CAS Number
9001-60-9
Activity
1270 U/vial (Dimensionl (R) Clinical Chemistry System)
Preparation and Storage
At -20 degree C
Storage Note: Protect from moisture
Related Product Information for LAD active protein
AAA Biotech produces bovine heart Lactate Dehydrogenase (LDH) for medical research, life science and manufacturing uses.

Custom preparations, technical support, bulk quantities and aliquoting available.

Our Lactate Dehydrogenase is used in multi-analyte clinical chemistry controls and calibrators by major IVD manufacturers worldwide.

Lactate dehydrogenase is an enzyme present in a wide variety of organisms, including plants and animals. Determination of serum lacate dehydrogenase activity is one of the most frequently performed assays as an aid in the identification of myocardial and pulmonary infarction.

Other conditions, such as megaloblasic anemia, extensive carcinomatois, severe shock and hypoxia, granulocytic or aute anemia, hemolytic anemia, infectious mononucleosis, preogressive musclar dystrophy, hepatitis, cirrhosis, obstructive jaundice, and in delirium tremens are all caused increased activity of lacate dehydrogenase activity

LDH is also found in cerebrospinal fluid where high levels of lactate dehydrogenase in cerebrospinal fluid are often associated with bacterial meningitis. High levels can also be found in cases of viral meningitis, generally indicating the presence of encephalitis and poor prognosis.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
~136,700
NCBI Official Full Name
lactate dehydrogenase
NCBI Official Symbol
Ldh
NCBI Protein Information
lactate dehydrogenase

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Product Notes

The LAD (Catalog #AAA44807) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Lactate Dehydrogenase, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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