Standard Curve (Sample)
Mouse LDL Receptor ELISA Kit | LDLR elisa kit
Mouse LDL Receptor ELISA Kit
Gene Names
Ldlr; Hlb301
Reactivity
Mouse
Synonyms
LDL Receptor; N/A; Mouse LDL Receptor ELISA Kit; Low-density lipoprotein receptor; LDL receptor; LDLR elisa kit
Reactivity
Mouse
Specificity
The Mouse LDL Receptor ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Mouse LDL Receptor proteins within the range of 62.5 pg/ml - 4000 pg/ml.
Sequence Length
810
Samples
Cell Culture Supernates, Serum, Plasma, Urine
Sensitivity
<12 pg/ml
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Standard Curve (Sample)
Standard Curve (Sample)
Related Product Information for LDLR elisa kit
Principle of the Assay: The Mouse LDL Receptor ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Mouse LDL Receptor in Cell Culture Supernates, Serum, Plasma, Urine. This assay employs an antibody specific for Mouse LDL Receptor coated on a 96-well plate. Standards and samples are pipetted into the wells and LDL Receptor present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Mouse LDL Receptor antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of LDL Receptor bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.
Background: The Low-Density Lipoprotein (LDL) Receptor is a mosaic protein of 839 amino acids (after removal of 21-amino acid signal peptide) that mediates the endocytosis of cholesterol-rich LDL. In humans, the LDL receptor protein is encoded by the LDLR gene. It belongs to the Low density lipoprotein receptor gene family. The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.
Background: The Low-Density Lipoprotein (LDL) Receptor is a mosaic protein of 839 amino acids (after removal of 21-amino acid signal peptide) that mediates the endocytosis of cholesterol-rich LDL. In humans, the LDL receptor protein is encoded by the LDLR gene. It belongs to the Low density lipoprotein receptor gene family. The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
94,947 Da
NCBI Official Full Name
low-density lipoprotein receptor isoform 2
NCBI Official Synonym Full Names
low density lipoprotein receptor
NCBI Official Symbol
Ldlr
NCBI Official Synonym Symbols
Hlb301
NCBI Protein Information
low-density lipoprotein receptor
UniProt Protein Name
Low-density lipoprotein receptor
UniProt Gene Name
Ldlr
UniProt Synonym Gene Names
LDL receptor
UniProt Entry Name
LDLR_MOUSE
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Product Notes
The Mouse LDLR ldlr (Catalog #AAA263128) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA263128 ELISA Kit recognizes Mouse LDLR. It is sometimes possible for the material contained within the vial of "LDL Receptor, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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