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product-image-AAA109727_WB13.jpg WB (Western Blot) (Western blot analysis of extracts from HeLa cells, treated with etoposide (25muM, 1hour), using Lamin A (cleaved-Asp230) antibody.)

anti-Mouse, Rat Lamin A Antibody | anti-LMNA antibody

Lamin A (Cleaved-Asp230) Antibody

Gene Names
LMNA; FPL; IDC; LFP; CDDC; EMD2; FPLD; HGPS; LDP1; LMN1; LMNC; MADA; PRO1; CDCD1; CMD1A; FPLD2; LMNL1; CMT2B1; LGMD1B
Reactivity
Mouse, Rat
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
Lamin A; N/A; Lamin A (Cleaved-Asp230) Antibody; 70 kDa lamin; LAMA; LMN1; anti-LMNA antibody
Ordering
Reactivity
Mouse, Rat
Specificity
Lamin A (cleaved-Asp230) antibody detects endogenous levels of fragment of activated Lamin A resulting from cleavage adjacent to Asp230.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
574
Applicable Applications for anti-LMNA antibody
ELISA, IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
The antiserum was produced against synthesized peptide derived from human Lamin A.
All Sites
Human: Asp230
Mouse: Asp230
Rat: Asp229
Preparation and Storage
Store at-20 degree C for 1 year

WB (Western Blot)

(Western blot analysis of extracts from HeLa cells, treated with etoposide (25muM, 1hour), using Lamin A (cleaved-Asp230) antibody.)

product-image-AAA109727_WB13.jpg WB (Western Blot) (Western blot analysis of extracts from HeLa cells, treated with etoposide (25muM, 1hour), using Lamin A (cleaved-Asp230) antibody.)

IHC (Immunohistochemistry)

(Cl-peptide-+ Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Lamin A (cleaved-Asp230) antibody.)

product-image-AAA109727_IHC15.jpg IHC (Immunohistochemistry) (Cl-peptide-+ Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Lamin A (cleaved-Asp230) antibody.)
References
Revekka L. Boguslavsky, Hum. Mol. Genet., Feb 2006; 15: 653-663. Dan Constantinescu, Stem Cells, Jan 2006; 24: 177-185. Richard L. Frock, Genes & Dev., Feb 2006; 20: 486-500. Jan Lammerding, J. Biol. Chem., Sep 2006; 281: 25768-25780.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
69,249 Da
NCBI Official Full Name
lamin isoform D
NCBI Official Synonym Full Names
lamin A/C
NCBI Official Symbol
LMNA
NCBI Official Synonym Symbols
FPL; IDC; LFP; CDDC; EMD2; FPLD; HGPS; LDP1; LMN1; LMNC; MADA; PRO1; CDCD1; CMD1A; FPLD2; LMNL1; CMT2B1; LGMD1B
NCBI Protein Information
lamin
UniProt Protein Name
Prelamin-A/C
UniProt Gene Name
LMNA
UniProt Synonym Gene Names
LMN1

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Product Notes

The LMNA lmna (Catalog #AAA109727) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Lamin A (Cleaved-Asp230) Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Lamin A can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the LMNA lmna for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lamin A, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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