Application Data
LRP1 recombinant protein
Recombinant Human LRP1 Protein (Cluster II, hFc Tag), HPLC-verified
Gene Names
LRP1; APR; LRP; A2MR; CD91; APOER; LRP1A; TGFBR5; IGFBP3R
Reactivity
Human
Purity
>= 95% as determined by SDS-PAGE. >= 95% as determined by SEC-HPLC.
Synonyms
LRP1; N/A; Recombinant Human LRP1 Protein (Cluster II, hFc Tag), HPLC-verified; Human LRP1 Protein (Cluster II, Fc Tag); low density lipoprotein receptor-related protein 1; A2MR Protein, Human; APOER Protein, Human; APR Protein, Human; CD91 Protein, Human; DDH3 Protein, Human; IGFBP-3R Protein, Human; IGFBP3R Protein, Human; IGFBP3R1 Protein, Human; KPA Protein, Human; LRP Protein, Human; LRP1A Protein, Human; TGFBR5 Protein, Human; LRP1 recombinant protein
Host
HEK293 Cells
Reactivity
Human
Purity/Purification
>= 95% as determined by SDS-PAGE. >= 95% as determined by SEC-HPLC.
Form/Format
Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Sequence
Arg786-Leu1165
Tag
C-human IgG1-Fc
Predicted N Terminal
Arg 786
Endotoxin
< 1.0 EU perug of the protein as determined by the LAL method
Protein Construction
A DNA sequence encoding the Human LRP1 (Q07954)(Arg786-Leu1165) was expressed with the Fc region of human IgG1 at the C-terminus.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Application Data
Application Data
Application Data
Application Data
Related Product Information for LRP1 recombinant protein
Low-density lipoprotein receptor-related protein 1 (LRP1), also known as alpha-2-macroglobulin receptor (A2MR), apolipoprotein E receptor (APOER), or cluster of differentiation 91 (CD91), is an endocytic receptor involved in several cellular processes. LRP1/CD91 is a member of the cluster of differentiation (CD) system. The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins do not take part in the cell signal process but have other functions such as cell adhesion. LRP1/CD91 is involved in endocytosis and phagocytosis of apoptotic cells and is required for early embryonic development. LRP1/CD91 is also involved in cellular lipid homeostasis, the plasma clearance of chylomicron remnants, activated LRPAP1 (alpha 2-macroglobulin), and the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. LRP1/CD91 May modulate cellular events, such as APP metabolism kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission need the involvement of LRP1/CD91.
Product Categories/Family for LRP1 recombinant protein
References
S. HP. e. al. (2002. Interactio. o. CED-6/GULP. a. adapte. protei. involve. i. engulfmen. o. apoptoti. cell. wit. CED-. an. CD91/lo. densit. lipoprotei. receptor-relate. protei. (LRP). . Bio. Chem. 277(14). 11772-9.Che. JS. e. al. (2010. Secrete. hea. shoc. protei. 90alph. induce. colorecta. cance. cel. invasio. throug. CD91/LRP-. an. NF-kappaB-mediate. integri. alpha. expression. . Bio. Chem. 285(33). 25458-66.Dasgupt. S. e. al. (2008. Facto. VII. bypasse. CD91/LR. fo. endocytosi. b. dendriti. cell. leadin. t. T-cel. activation. Haematologica. 93(1). 83-9.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
504,606 Da
NCBI Official Full Name
prolow-density lipoprotein receptor-related protein 1
NCBI Official Synonym Full Names
low density lipoprotein receptor-related protein 1
NCBI Official Symbol
LRP1
NCBI Official Synonym Symbols
APR; LRP; A2MR; CD91; APOER; LRP1A; TGFBR5; IGFBP3R
NCBI Protein Information
prolow-density lipoprotein receptor-related protein 1; LRP-1; type V tgf-beta receptor; apolipoprotein E receptor; alpha-2-macroglobulin receptor; TbetaR-V/LRP-1/IGFBP-3 receptor
UniProt Protein Name
Prolow-density lipoprotein receptor-related protein 1
UniProt Gene Name
LRP1
UniProt Synonym Gene Names
A2MR; APR; LRP-1; A2MR; APOER; LRP-85; LRP-515; LRPICD
UniProt Entry Name
LRP1_HUMAN
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Product Notes
The LRP1 lrp1 (Catalog #AAA259288) is a Recombinant Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Human LRP1 Protein (Cluster II, hFc Tag), HPLC-verified reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: Arg786-Leu 1165. It is sometimes possible for the material contained within the vial of "LRP1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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