Application Data
LRRC32 recombinant protein
LRRC32 Protein, Mouse, Recombinant (ECD, hFc Tag), HPLC-verified
Gene Names
Lrrc32; Garp; AI426318; EG434215; D11S833Eh; D7H11S833E
Purity
>= 95% as determined by SDS-PAGE.= 90% as determined by SEC-HPLC.
Synonyms
LRRC32; N/A; LRRC32 Protein, Mouse, Recombinant (ECD, hFc Tag), HPLC-verified; leucine rich repeat containing 32; AI426318 Protein, Mouse; D11S833Eh Protein, Mouse; D7H11S833E Protein, Mouse; EG434215 Protein, Mouse; Garp Protein, Mouse; LRRC32 recombinant protein
Host
HEK293 Cells
Purity/Purification
>= 95% as determined by SDS-PAGE.
= 90% as determined by SEC-HPLC.
= 90% as determined by SEC-HPLC.
Form/Format
Lyophilized from sterile PBS, pH 7.4, 5% trehalose.
Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Species
Mouse
Predicted N Terminal
Ile 18
Endotoxin
<1.0 EU per ug protein as determined by the LAL method.
Protein Construction
A DNA sequence encoding the Mouse LRRC32 (G3XA59)(Met1-Asn628) was expressed with the Fc region of human IgG1 at the C-terminus.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Application Data
Application Data
Application Data
Application Data
Related Product Information for LRRC32 recombinant protein
LRRC32 (Leucine-Rich Repeat Containing 32) is a Protein Coding gene. This gene encodes a type I membrane protein which contains 20 leucine-rich repeats. LRRC32, also known as Glycoprotein A Repetitions Predominant (GARP), has been postulated as a novel surface marker of activated T(regs). LRRC32 is a T(reg)-specific receptor that binds latent TGF-beta and dominantly controls FOXP3 and the regulatory phenotype via a positive feedback loop. It belongs to the LRRC32/LRRC33 family and is broadly expressed in the placenta, lung, and other tissues. Alterations in the chromosomal region 11q13-11q14 are involved in several pathologies. An important paralog of this gene is NRROS.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
72,418 Da
NCBI Official Full Name
leucine-rich repeat-containing protein 32
NCBI Official Synonym Full Names
leucine rich repeat containing 32
NCBI Official Symbol
Lrrc32
NCBI Official Synonym Symbols
Garp; AI426318; EG434215; D11S833Eh; D7H11S833E
NCBI Protein Information
leucine-rich repeat-containing protein 32
UniProt Protein Name
Leucine-rich repeat-containing 32
UniProt Gene Name
Lrrc32
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Product Notes
The LRRC32 lrrc32 (Catalog #AAA259276) is a Recombinant Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "LRRC32, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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