WB (Western Blot)
(Figure 2: Western blot analysis using anti-ACE2 (human), mAb (AC18F) at 1: 2,000 dilution.; 1. hACE2 (Fc protein).; 2. hACE2 (Ecto domain) (DYKDDDDK-tagged).; 3. Other hGITR (Fc protein) (control).)
Mouse anti-Human ACE-2 Monoclonal Antibody | anti-ACE-2 antibody
anti-ACE2, mAb (Clone: AC18F)
Gene Names
ACE2; ACEH
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Western Blot, ELISA
Purity
Protein G-affinity purified
Synonyms
ACE-2, Antibody; anti-ACE2, mAb (Clone: AC18F); Angiotensin-converting enzyme 2; anti-ACE-2 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
AC18F
Specificity
Recognizes human ACE2.
Purity/Purification
Protein G-affinity purified
Form/Format
Purified. Liquid. 0.2um-filtered solution in PBS, pH7.4. Contains no preservatives.
Concentration
1mg/ml (varies by lot)
Sequence Length
805
Applicable Applications for anti-ACE-2 antibody
FCM/FACS (Flow Cytometry), WB (Western Blot), ELISA
Immunogen
Recombinant human ACE2
Antigen
ACE2
Preparation and Storage
Short Term Storage: 4 degree C
Long Term Storage: -20 degree C
After opening, prepare aliquots and store at -20 degree C.
Avoid freeze/thaw cycles.
Long Term Storage: -20 degree C
After opening, prepare aliquots and store at -20 degree C.
Avoid freeze/thaw cycles.
WB (Western Blot)
(Figure 2: Western blot analysis using anti-ACE2 (human), mAb (AC18F) at 1: 2,000 dilution.; 1. hACE2 (Fc protein).; 2. hACE2 (Ecto domain) (DYKDDDDK-tagged).; 3. Other hGITR (Fc protein) (control).)
WB (Western Blot)
(Figure 2: Western blot analysis using anti-ACE2 (human), mAb (AC18F) at 1: 2,000 dilution.; 1. hACE2 (Fc protein).; 2. hACE2 (Ecto domain) (DYKDDDDK-tagged).; 3. Other hGITR (Fc protein) (control).)
FCM/FACS (Flow Cytometry)
(Figure 1: FACS: Cell Surface staining of human ACE2 on HepG2 cell line. Red: Human anti-ACE2 antibody (Clone:AC18F), 1ug/10^6 cells were used. Green : Isotype control, mouse IgG1, 1ug/ 10^6 cells was used as control. PE conjugated Goat anti-mouse IgG was used as secondary antibody.)
FCM/FACS (Flow Cytometry)
(Figure 1: FACS: Cell Surface staining of human ACE2 on HepG2 cell line. Red: Human anti-ACE2 antibody (Clone:AC18F), 1ug/10^6 cells were used. Green : Isotype control, mouse IgG1, 1ug/ 10^6 cells was used as control. PE conjugated Goat anti-mouse IgG was used as secondary antibody.)
Related Product Information for anti-ACE-2 antibody
Angiotensin-converting enzyme2 (ACE2) is an ectoenzyme (carboxypeptidase) with an extracellular catalytic domain that predominantly localizes at the plasma membrane and is thereby able to hydrolyze circulating peptides. ACE2 has approximately 42% sequence identity with ACE, and its cytoplasmic and transmembrane domains show 48% homology to the protein collectrin that plays a critical role in the amino acid absorption of the kidney. ACE2 converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. ACE2 is involved in the regulation of systemic blood pressure and has direct effects on cardiac functions. It is expressed predominantly in endothelial cells of the lung, gut, heart and kidney. ACE2 together with the protease TMPRSS2 acts as a functional receptor for SARS coronavirus as well as for the new highly pathogenic coronavirus, 2019-nCoV/SARS-CoV-2, which is cause for pneumonia COVID-19.
Product Categories/Family for anti-ACE-2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
angiotensin-converting enzyme 2
NCBI Official Synonym Full Names
angiotensin I converting enzyme 2
NCBI Official Symbol
ACE2
NCBI Official Synonym Symbols
ACEH
NCBI Protein Information
angiotensin-converting enzyme 2
UniProt Protein Name
Angiotensin-converting enzyme 2
UniProt Gene Name
ACE2
UniProt Synonym Gene Names
ACEH
UniProt Entry Name
ACE2_HUMAN
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Product Notes
The ACE-2 ace2 (Catalog #AAA78522) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The anti-ACE2, mAb (Clone: AC18F) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ACE-2 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the ACE-2 ace2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ACE-2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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