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product-image-AAA51859_IHC11.jpg IHC (Immunohistochemisry) (Paraffin sections of striated muscle (below) from human tongue immunostained with 3B3 (1:250))

Mouse ACTA1 / ASMA Monoclonal Antibody | anti-ACTA1 antibody

Mouse Monoclonal [clone 3B3] (IgG1) to Human ACTA1 / ASMA

Gene Names
ACTA1; ACTA; ASMA; CFTD; MPFD; NEM1; NEM2; NEM3; CFTD1; CFTDM
Reactivity
Goat, Human, Pig, Rabbit, Rat
Applications
ELISA, Western Blot, Immunohistochemistry, Immunohistochemistry
Purity
Purified
Synonyms
ACTA1 / ASMA, Antibody; Mouse Monoclonal [clone 3B3] (IgG1) to Human ACTA1 / ASMA; Anti-ACTA1 / ASMA Antibody (clone 3B3) IHC-plus; ACTA1; ACTA; Actin; alpha skeletal muscle; Alpha-actin-1; CFTD; CFTD1; CFTDM; MPFD; NEM1; NEM2; ASMA; NEM3; Human ACTA1; anti-ACTA1 antibody
Ordering
Host
Mouse
Reactivity
Goat, Human, Pig, Rabbit, Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3B3
Specificity
Highly specific for alpha- skeletal actin, and does not cross react with other actin isoforms. The epitope recognized by 3B3 is highly conserved. Therefore the antibody cross-reacts with many other species.
Purity/Purification
Purified
Form/Format
PBS containing 0.09% sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
377
Applicable Applications for anti-ACTA1 antibody
ELISA, WB (Western Blot), IHC (Immunohistochemistry), IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
Peptide comprising the N-terminal nonapeptide of alpha-skeletal actin with an acetylated N-terminus (Ac-DEDETTALVC-COOH) coupled to keyhole limpet hemocyanin through the cysteine residue
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.

IHC (Immunohistochemisry)

(Paraffin sections of striated muscle (below) from human tongue immunostained with 3B3 (1:250))

product-image-AAA51859_IHC11.jpg IHC (Immunohistochemisry) (Paraffin sections of striated muscle (below) from human tongue immunostained with 3B3 (1:250))

IHC (Immunohiostchemistry)

(Paraffin sections of human striated skeletal muscle immunostained with 3B3 (1:250))

product-image-AAA51859_IHC13.jpg IHC (Immunohiostchemistry) (Paraffin sections of human striated skeletal muscle immunostained with 3B3 (1:250))

IHC (Immunohistochemistry)

(Anti-ACTA1 / ASMA antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

product-image-AAA51859_IHC15.jpg IHC (Immunohistochemistry) (Anti-ACTA1 / ASMA antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Related Product Information for anti-ACTA1 antibody
Actin alpha 1 which is expressed in skeletal muscle is one of six different actin isoforms which have been identified. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus. The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
58
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,051 Da
NCBI Official Full Name
actin, alpha skeletal muscle
NCBI Official Synonym Full Names
actin, alpha 1, skeletal muscle
NCBI Official Symbol
ACTA1
NCBI Official Synonym Symbols
ACTA; ASMA; CFTD; MPFD; NEM1; NEM2; NEM3; CFTD1; CFTDM
NCBI Protein Information
actin, alpha skeletal muscle; nemaline myopathy type 3
UniProt Protein Name
Actin, alpha skeletal muscle
UniProt Gene Name
ACTA1
UniProt Synonym Gene Names
ACTA
UniProt Entry Name
ACTS_HUMAN

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Product Notes

The ACTA1 acta1 (Catalog #AAA51859) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone 3B3] (IgG1) to Human ACTA1 / ASMA reacts with Goat, Human, Pig, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ACTA1 / ASMA can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot), IHC (Immunohistochemistry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the ACTA1 acta1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ACTA1 / ASMA, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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