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Mouse anti-Human Afelimomab Monoclonal Antibody | anti-TNF antibody

Research Grade Afelimomab

Gene Names
TNF; DIF; TNFA; TNFSF2; TNF-alpha
Reactivity
Human
Purity
>95%; Protein A or G purified from cell culture supernatant.
Synonyms
Afelimomab, Antibody; Research Grade Afelimomab; MAK-195F; TNF; Tumor necrosis factor ligand superfamily member 2; N-terminal fragment; ICD2; NTF; TNF-a; TNF-alpha; Tumor necrosis factor; TNFSF2; TNFA; Cachectin; ICD1; anti-TNF antibody
Ordering
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Purity/Purification
>95%; Protein A or G purified from cell culture supernatant.
Form/Format
Liquid. PBS buffer, pH7.4
Concentration
1mg/ml (varies by lot)
CAS
156227-98-4
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at +4 degree C short term (1-2 weeks). Store at -20 degree C 12 months. Store at -80 degree C long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Product Categories/Family for anti-TNF antibody
References
[Anti-inflammatory treatment in sepsis], PMID: 12430058
A multicenter, open-label, prospective, randomized, dose-ranging pharmacokinetic study of the anti-TNF-alpha antibody afelimomab in patients with sepsis syndrome, PMID: 11534565
Afelimomab led to a modest mortality benefit in patients with severe sepsis and elevated interleukin-6 levels, PMID: 16277704
Afelimomab, PMID: 10829362
Afelimomab-another therapeutic option in sepsis therapy, PMID: 15640652

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25,644 Da
NCBI Official Full Name
tumor necrosis factor
NCBI Official Synonym Full Names
tumor necrosis factor
NCBI Official Symbol
TNF
NCBI Official Synonym Symbols
DIF; TNFA; TNFSF2; TNF-alpha
NCBI Protein Information
tumor necrosis factor; TNF-a; cachectin; APC1 protein; TNF, monocyte-derived; TNF, macrophage-derived; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2
UniProt Protein Name
Tumor necrosis factor
UniProt Gene Name
TNF
UniProt Synonym Gene Names
TNFA; TNFSF2; TNF-a; NTF; ICD1; ICD2
UniProt Entry Name
TNFA_HUMAN

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Product Notes

The TNF tnf (Catalog #AAA119978) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Research Grade Afelimomab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Afelimomab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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