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IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded Human Kidney stained with AIF1 / Iba1 Mouse Monoclonal Antibody (AIF1/1909).)
Mouse AIF1/Iba1 Monoclonal Antibody | anti-AIF1 antibody
AIF1/Iba1 (Microglia Marker)
Gene Names
AIF1; IBA1; IRT1; AIF-1; IRT-1
Reactivity
Human. Others not known.
Applications
Immunohistochemistry
Synonyms
AIF1/Iba1, Antibody; AIF1/Iba1 (Microglia Marker); Allograft inflammatory factor 1 (AIF1); balloon angioplasty responsive transcription (BART1); IBA1; Interferon responsive transcript 1; Ionized calcium-binding adapter molecule 1; IRT1; Microglia response factor (MRF1); anti-AIF1 antibody
Host
Mouse
Reactivity
Human. Others not known.
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone Number
AIF1/1909
Specificity
AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
93
Applicable Applications for anti-AIF1 antibody
IHC (Immunohistochemistry)
Immunogen
Purified recombinant human AIF1 protein (around aa 1-146)
Cellular Localization
Cytoplasmic and Cell Surface
Hu-chromosome Location
6p21.33
Positive Control
Lymph Node, Tonsil or Kidney
Preparation and Storage
Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded Human Kidney stained with AIF1 / Iba1 Mouse Monoclonal Antibody (AIF1/1909).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded Human Kidney stained with AIF1 / Iba1 Mouse Monoclonal Antibody (AIF1/1909).)
IHC (Immunohistochemisry)
(Formalin-fixed, paraffin-embedded Human Lymph Node stained with AIF1 / Iba1 Mouse Monoclonal Antibody (AIF1/1909).)
IHC (Immunohistochemisry)
(Formalin-fixed, paraffin-embedded Human Lymph Node stained with AIF1 / Iba1 Mouse Monoclonal Antibody (AIF1/1909).)
Application Data
(Purified AIF1 / Iba1 Mouse Monoclonal Antibody (AIF1/1909). Confirmation of Integrity and Purity of Antibody.)
Application Data
(Purified AIF1 / Iba1 Mouse Monoclonal Antibody (AIF1/1909). Confirmation of Integrity and Purity of Antibody.)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Tonsil stained with AIF1 / Iba1 Mouse Monoclonal Antibody (AIF1/1909).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Tonsil stained with AIF1 / Iba1 Mouse Monoclonal Antibody (AIF1/1909).)
References
Kelemen SE, Autieri MV.Expression of allograft inflammatory factor-1 in T lymphocytes.Am J Pathol2005; 167:619-26.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
17kDa
NCBI Official Full Name
allograft inflammatory factor 1 isoform 1
NCBI Official Synonym Full Names
allograft inflammatory factor 1
NCBI Official Symbol
AIF1
NCBI Official Synonym Symbols
IBA1; IRT1; AIF-1; IRT-1
NCBI Protein Information
allograft inflammatory factor 1
UniProt Protein Name
Allograft inflammatory factor 1
UniProt Gene Name
AIF1
UniProt Synonym Gene Names
G1; IBA1; AIF-1
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Product Notes
The AIF1 aif1 (Catalog #AAA62960) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The AIF1/Iba1 (Microglia Marker) reacts with Human. Others not known. and may cross-react with other species as described in the data sheet. AAA Biotech's AIF1/Iba1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the AIF1 aif1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AIF1/Iba1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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