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product-image-AAA120078_SDS_PAGE13.jpg SDS-PAGE (SDS PAGE for Alacizumab)

anti-Human Alacizumab Monoclonal Antibody | anti-KDR antibody

Research Grade Alacizumab

Gene Names
KDR; FLK1; CD309; VEGFR; VEGFR2
Reactivity
Human
Purity
>95%; Protein A or G purified from cell culture supernatant.
Synonyms
Alacizumab, Antibody; Research Grade Alacizumab; FLK-1; Kinase insert domain receptor; VEGFR2; Fetal liver kinase 1; CD309; Vascular endothelial growth factor receptor 2; Protein-tyrosine kinase receptor flk-1; FLK1; VEGFR-2; KDR; anti-KDR antibody
Ordering
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG4
Purity/Purification
>95%; Protein A or G purified from cell culture supernatant.
Form/Format
Liquid. PBS buffer, pH7.4
Concentration
1mg/ml (varies by lot)
Host Species
Humanized
Expression system
Mammalian cells
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at +4 degree C short term (1-2 weeks). Store at -20 degree C 12 months. Store at -80 degree C long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

SDS-PAGE

(SDS PAGE for Alacizumab)

product-image-AAA120078_SDS_PAGE13.jpg SDS-PAGE (SDS PAGE for Alacizumab)

Bioactivity

(Detects Human CD309/KDR/VEGFR-2 in direct ELISAs.)

product-image-AAA120078_BIOACTIVITY15.jpg Bioactivity (Detects Human CD309/KDR/VEGFR-2 in direct ELISAs.)
Product Categories/Family for anti-KDR antibody
References
Caplacizumab: First Global Approval, PMID: 30298461
Caplacizumab for Acquired Thrombotic Thrombocytopenic Purpura, PMID: 26863353
Caplacizumab in adult patients with acquired thrombotic thrombocytopenic purpura, PMID: 32095224
Caplacizumab: an anti-von Willebrand factor antibody for the treatment of thrombotic thrombocytopenic purpura, PMID: 32588878
Caplacizumab: a change in the paradigm of thrombotic thrombocytopenic purpura treatment, PMID: 31359806

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
151,527 Da
NCBI Official Full Name
vascular endothelial growth factor receptor 2
NCBI Official Synonym Full Names
kinase insert domain receptor (a type III receptor tyrosine kinase)
NCBI Official Symbol
KDR
NCBI Official Synonym Symbols
FLK1; CD309; VEGFR; VEGFR2
NCBI Protein Information
vascular endothelial growth factor receptor 2; soluble VEGFR2; fetal liver kinase 1; fetal liver kinase-1; protein-tyrosine kinase receptor Flk-1; tyrosine kinase growth factor receptor
UniProt Protein Name
Vascular endothelial growth factor receptor 2
UniProt Gene Name
KDR
UniProt Synonym Gene Names
FLK1; VEGFR2; VEGFR-2; FLK-1; KDR
UniProt Entry Name
VGFR2_HUMAN

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Product Notes

The KDR kdr (Catalog #AAA120078) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Research Grade Alacizumab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Alacizumab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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